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Janel L. Kopp, Ph.D.

Affiliations: 
2007 University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Molecular Biology
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"Janel Kopp"
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Angie Rizzino grad student 2007 University of Nebraska Medical Center
 (Autoinhibitory domains: A mechanism for ETS transcription factor specificity.)

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Espinet E, Gu Z, Imbusch CD, et al. (2020) Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell-of-origin. Cancer Discovery
Ye J, Huang A, Wang H, et al. (2020) PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response. Cell Death & Disease. 11: 187
Das KK, Heeg S, Pitarresi JR, et al. (2018) ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis. Developmental Dynamics : An Official Publication of the American Association of Anatomists
Lee AYL, Dubois CL, Sarai K, et al. (2018) Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma. Gut
Kopp JL, Dubois CL, Schaeffer DF, et al. (2017) Loss of PTEN and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice. Gastroenterology
Barrionuevo FJ, Hurtado A, Kim GJ, et al. (2016) Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration. Elife. 5
Fox RG, Lytle NK, Jaquish DV, et al. (2016) Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma. Nature
Kopp JL, Grompe M, Sander M. (2016) Stem cells versus plasticity in liver and pancreas regeneration. Nature Cell Biology. 18: 238-45
Lee A, Dubois C, Schaeffer D, et al. (2016) Abstract A84: PDAC initiation and progression occurs more rapidly from KrasG12D-expressing ductal cells than KrasG12D-expressing acinar cells in the absence of Trp53 Cancer Research. 76
Font-Burgada J, Shalapour S, Ramaswamy S, et al. (2015) Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer. Cell. 162: 766-79
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