Kenneth L. Friedrich, Ph.D.

Affiliations: 
2003 University of Arizona, Tucson, AZ 
Area:
Biochemistry
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"Kenneth Friedrich"
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Elizabeth Vierling grad student 2003 University of Arizona
 (Dynamic behavior of small heat shock protein subunits and their interactions with substrates.)
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Publications

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Basha E, Friedrich KL, Vierling E. (2006) The N-terminal arm of small heat shock proteins is important for both chaperone activity and substrate specificity. The Journal of Biological Chemistry. 281: 39943-52
Ambrus A, Friedrich K, Somogyi A. (2006) Oligomerization of nitrophorins. Analytical Biochemistry. 352: 286-95
Wilkinson KD, Ventii KH, Friedrich KL, et al. (2005) The ubiquitin signal: assembly, recognition and termination. Symposium on ubiquitin and signaling. Embo Reports. 6: 815-20
Friedrich KL, Giese KC, Buan NR, et al. (2004) Interactions between small heat shock protein subunits and substrate in small heat shock protein-substrate complexes. The Journal of Biological Chemistry. 279: 1080-9
Wintrode PL, Friedrich KL, Vierling E, et al. (2003) Solution structure and dynamics of a heat shock protein assembly probed by hydrogen exchange and mass spectrometry. Biochemistry. 42: 10667-73
Mogk A, Schlieker C, Friedrich KL, et al. (2003) Refolding of substrates bound to small Hsps relies on a disaggregation reaction mediated most efficiently by ClpB/DnaK. The Journal of Biological Chemistry. 278: 31033-42
van Montfort RL, Basha E, Friedrich KL, et al. (2001) Crystal structure and assembly of a eukaryotic small heat shock protein. Nature Structural Biology. 8: 1025-30
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