Timothy M. Pabst, Ph.D.
Affiliations: | 2008 | University of Virginia, Charlottesville, VA |
Area:
Chemical Engineering, Biochemistry, Analytical ChemistryGoogle:
"Timothy Pabst"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Giorgio Carta | grad student | 2008 | UVA | |
| (pH transitions, protein separations, and mass transfer in chromatography columns containing weak ion exchange groups.) | ||||
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Publications
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| Luo H, Du Q, Qian C, et al. (2022) Formation of transient highly-charged mAb clusters strengthens interactions with host cell proteins and results in poor clearance of host cell proteins by protein A chromatography. Journal of Chromatography. A. 1679: 463385 |
| Kimerer LK, Pabst TM, Hunter AK, et al. (2021) Role of configurational flexibility on the adsorption kinetics of bivalent bispecific antibodies on porous cation exchange resins. Journal of Chromatography. A. 1655: 462479 |
| Kimerer LK, Niu B, Pabst TM, et al. (2021) Chromatographic and adsorptive behavior of a bivalent bispecific antibody and associated fragments. Journal of Chromatography. A. 1648: 462181 |
| Kimerer LK, Pabst TM, Hunter AK, et al. (2020) Chromatographic behavior of bivalent bispecific antibodies on hydrophobic interaction chromatography columns. Journal of Chromatography. A. 460836 |
| Kimerer LK, Pabst TM, Hunter AK, et al. (2019) Chromatographic behavior of bivalent bispecific antibodies on cation exchange columns. I. Experimental observations and phenomenological model. Journal of Chromatography. A |
| Kimerer LK, Pabst TM, Hunter AK, et al. (2019) Chromatographic behavior of bivalent bispecific antibodies on cation exchange columns. II. Biomolecular perspectives. Journal of Chromatography. A |
| Du Q, Damschroder M, Pabst TM, et al. (2019) Process optimization and protein engineering mitigated manufacturing challenges of a monoclonal antibody with liquid-liquid phase separation issue by disrupting inter-molecule electrostatic interactions. Mabs |
| Luo H, Tie L, Cao M, et al. (2018) Cathepsin L Causes Proteolytic Cleavage of CHO Expressed Proteins During Processing and Storage: Identification, Characterization, and Mitigation. Biotechnology Progress |
| Creasy A, Reck J, Pabst T, et al. (2018) Systematic Interpolation Method Predicts Antibody Monomer-Dimer Separation by Gradient Elution Chromatography at High Protein Loads. Biotechnology Journal. e1800132 |
| Pabst TM, Thai J, Hunter AK. (2018) Evaluation of recent Protein A stationary phase innovations for capture of biotherapeutics. Journal of Chromatography. A |