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Zayna A. Khayat, Ph.D.

Affiliations: 
2001 University of Toronto, Toronto, ON, Canada 
Area:
Cell Biology
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"Zayna Khayat"
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Amira Klip grad student 2001 University of Toronto
 (Multiple mechanisms of regulating glucose transporters and glucose transport in skeletal muscle cells.)

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Patel N, Rudich A, Khayat ZA, et al. (2003) Intracellular segregation of phosphatidylinositol-3,4,5-trisphosphate by insulin-dependent actin remodeling in L6 skeletal muscle cells. Molecular and Cellular Biology. 23: 4611-26
Khayat ZA, Patel N, Klip A. (2002) Exercise- and insulin-stimulated muscle glucose transport: distinct mechanisms of regulation. Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie AppliquéE. 27: 129-51
Tong P, Khayat ZA, Huang C, et al. (2001) Insulin-induced cortical actin remodeling promotes GLUT4 insertion at muscle cell membrane ruffles. The Journal of Clinical Investigation. 108: 371-81
Patel N, Khayat ZA, Ruderman NB, et al. (2001) Dissociation of 5' AMP-activated protein kinase activation and glucose uptake stimulation by mitochondrial uncoupling and hyperosmolar stress: differential sensitivities to intracellular Ca2+ and protein kinase C inhibition. Biochemical and Biophysical Research Communications. 285: 1066-70
Randhawa VK, Bilan PJ, Khayat ZA, et al. (2000) VAMP2, but not VAMP3/cellubrevin, mediates insulin-dependent incorporation of GLUT4 into the plasma membrane of L6 myoblasts. Molecular Biology of the Cell. 11: 2403-17
Khayat ZA, Tong P, Yaworsky K, et al. (2000) Insulin-induced actin filament remodeling colocalizes actin with phosphatidylinositol 3-kinase and GLUT4 in L6 myotubes. Journal of Cell Science. 113: 279-90
Khayat ZA, Tsakiridis T, Ueyama A, et al. (1998) Rapid stimulation of glucose transport by mitochondrial uncoupling depends in part on cytosolic Ca2+ and cPKC. The American Journal of Physiology. 275: C1487-97
Khayat ZA, McCall AL, Klip A. (1998) Unique mechanism of GLUT3 glucose transporter regulation by prolonged energy demand: increased protein half-life. The Biochemical Journal. 333: 713-8
Wang Q, Khayat Z, Kishi K, et al. (1998) GLUT4 translocation by insulin in intact muscle cells: Detection by a fast and quantitative assay Febs Letters. 427: 193-197
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