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Yongtao Li, Ph.D.

Affiliations: 
2003 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Biomedical Engineering
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Victor C. Yang grad student 2003 University of Michigan
 (Strategies for enhancing enzyme delivery using the heparin/protamine-based drug delivery system.)

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Publications

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Li YT, Kwon YM, Spangrude GJ, et al. (2009) Preliminary in vivo evaluation of the protein transduction domain-modified ATTEMPTS approach in enhancing asparaginase therapy. Journal of Biomedical Materials Research. Part A. 91: 209-20
Kwon YM, Li Y, Naik S, et al. (2008) The ATTEMPTS delivery systems for macromolecular drugs. Expert Opinion On Drug Delivery. 5: 1255-66
Kwon YM, Li YT, Liang JF, et al. (2008) PTD-modified ATTEMPTS system for enhanced asparaginase therapy: a proof-of-concept investigation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 130: 252-8
Park YJ, Liang JF, Song H, et al. (2003) ATTEMPTS: a heparin/protamine-based triggered release system for the delivery of enzyme drugs without associated side-effects. Advanced Drug Delivery Reviews. 55: 251-65
Liang JF, Li YT, Song H, et al. (2002) ATTEMPTS: a heparin/protamine-based delivery system for enzyme drugs. Journal of Controlled Release : Official Journal of the Controlled Release Society. 78: 67-79
Liang JF, Park YJ, Song H, et al. (2001) ATTEMPTS: a heparin/protamine-based prodrug approach for delivery of thrombolytic drugs. Journal of Controlled Release : Official Journal of the Controlled Release Society. 72: 145-56
Liang JF, Li YT, Connell ME, et al. (2000) Synthesis and characterization of positively charged tPA as a prodrug using heparin/protamine-based drug delivery system. Aaps Pharmsci. 2: E7
Liang JF, Li YT, Yang VC. (2000) A novel approach for delivery of enzyme drugs: preliminary demonstration of feasibility and utility in vitro. International Journal of Pharmaceutics. 202: 11-20
Liang JF, Li YT, Yang VC. (2000) Biomedical application of immobilized enzymes. Journal of Pharmaceutical Sciences. 89: 979-90
Liang JF, Song H, Li YT, et al. (2000) A novel heparin/protamine-based pro-drug type delivery system for protease drugs. Journal of Pharmaceutical Sciences. 89: 664-73
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