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Robert H. Broyles

Affiliations: 
University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States 
Area:
Molecular Biology, Biochemistry
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Visar Belegu grad student 2004 University of Oklahoma Health Sciences Center
Daryl R. Baker grad student 2007 University of Oklahoma Health Sciences Center

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Broyles RH, Joshi SK, Curtis CD, et al. (2014) Edx-17: A Novel, Safe and Efficacious Treatment for Sickle Cell Disease Blood. 124: 1357-1357
Broyles R, Belegu V, Roth A, et al. (2010) A developmental switch yields a treatment for beta thalassemias and sickle cell disease Developmental Biology. 344: 525
Broyles RH, Roth AC, Todd M, et al. (2006) Nuclear reprogramming by cell fusion. Methods in Molecular Biology (Clifton, N.J.). 325: 47-57
Broyles RH, Belegu V, Roth AC, et al. (2006) Ferritin Heavy Chain Stimulates HbS-to-HbF Switching in Erythroid Precursor Cells from Sickle Cell Patients. Blood. 108: 790-790
Broyles RH, Belegu V, Stewart CA, et al. (2004) Ferritin Heavy Chain, a Repressor of the Human β-Globin Gene That Binds a Conserved Cagtgc Motif, Is Bound to the Repressed β-Globin Promoter In Vivo in K562 Cells and Specifically Binds an Analogous Site in the Mouse β Major -Globin Promoter. Blood. 104: 1223-1223
Broyles RH, Belegu V, DeWitt CR, et al. (2001) Specific repression of beta-globin promoter activity by nuclear ferritin. Proceedings of the National Academy of Sciences of the United States of America. 98: 9145-50
Broyles RH. (1999) Use of somatic cell fusion to reprogram globin genes. Seminars in Cell & Developmental Biology. 10: 259-65
Broyles RH, Ramseyer LTH, Do TH, et al. (1994) Hemoglobin switching in Rana/Xenopus erythroid heterokaryons: Factors mediating the metamorphic hemoglobin switch are conserved Developmental Genetics. 15: 347-355
Ramseyer LTH, Barker-Harrel J, Smith DJ, et al. (1989) Intracellular signals for developmental hemoglobin switching Developmental Biology. 133: 262-271
Maples PB, Palmer JC, Broyles RH. (1988) Determination of hemoglobin expression patterns in erythroid cells of Rana catesbeiana tadpoles Comparative Biochemistry and Physiology -- Part B: Biochemistry And. 91: 755-762
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