Alan E. Tomkinson
Affiliations: | The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States |
Area:
Molecular Biology, BiochemistryGoogle:
"Alan Tomkinson"Mean distance: (not calculated yet)
Children
Sign in to add trainee| Zachary B. Mackey | grad student | 2000 | UT Health San Antonio |
| Teresa A. Motycka | grad student | 2004 | UT Health San Antonio |
| Hui-Min Tseng | grad student | 2004 | UT Health San Antonio |
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Publications
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| Kodavati M, Wang H, Guo W, et al. (2024) FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease. Nature Communications. 15: 2156 |
| Sallmyr A, Khattri Bhandari S, Naila T, et al. (2023) Mammalian DNA ligases; roles in maintaining genome integrity. Journal of Molecular Biology. 168276 |
| Hegde M, Manohar K, Wang H, et al. (2023) FUS Unveiled in Mitochondrial DNA Repair and Targeted Ligase-1 Expression Rescues Repair-Defects in FUS-Linked Neurodegeneration. Research Square |
| Bilkis R, Lake RJ, Cooper KL, et al. (2023) The CSB chromatin remodeler regulates PARP1- and PARP2-mediated single-strand break repair at actively transcribed DNA regions. Nucleic Acids Research |
| Chen S, Vogt A, Lee L, et al. (2023) Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ. Science Advances. 9: eadg2838 |
| Bhandari SK, Wiest N, Sallmyr A, et al. (2023) Unchanged PCNA and DNMT1 dynamics during replication in DNA ligase I-deficient cells but abnormal chromatin levels of non-replicative histone H1. Scientific Reports. 13: 4363 |
| Rashid I, Tsai MS, Sverzhinsky A, et al. (2022) Purification and Characterization of Human DNA Ligase IIIα Complexes After Expression in Insect Cells. Methods in Molecular Biology (Clifton, N.J.). 2444: 243-269 |
| Sverzhinsky A, Tomkinson AE, Pascal JM. (2021) Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. Structure (London, England : 1993) |
| Ali R, Alabdullah M, Algethami M, et al. (2021) Ligase 1 is a predictor of platinum resistance and its blockade is synthetically lethal in XRCC1 deficient epithelial ovarian cancers. Theranostics. 11: 8350-8361 |
| Rashid I, Hammel M, Sverzhinsky A, et al. (2021) Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III catalytic domain is regulated by phosphorylation of its flexible N-terminus. The Journal of Biological Chemistry. 100921 |