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Kandatege Wimalasena

Affiliations: 
Wichita State University, Wichita, KS, United States 
Area:
Biochemistry
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"Kandatege Wimalasena"
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Parents

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Sheldon W. May grad student 1986 Georgia Tech

Children

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Donovan C. Haines grad student 1994-1999 Wichita State University
Mehul Bhakta grad student 2004 Wichita State University
Ayodele O. Olabisi grad student 2005 Wichita State University

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Publications

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Lickteig B, Wimalasena VK, Wimalasena K. (2019) MPP+ Scaffold Containing Lipophilic Compounds are Potent Complex I Inhibitors and Selective Dopaminergic Toxins. Acs Chemical Neuroscience
Kadigamuwa CC, Mapa MS, Wimalasena K. (2016) Lipophilic Cationic Cyanines Are Potent Complex I Inhibitors and Specific in Vitro Dopaminergic Toxins with Mechanistic Similarities to Both Rotenone and MPP(.) Chemical Research in Toxicology
Wimalasena DS, Perera RP, Heyen BJ, et al. (2008) Vesicular monoamine transporter substrate/inhibitor activity of MPTP/MPP+ derivatives: a structure-activity study. Journal of Medicinal Chemistry. 51: 760-8
Bhakta MN, Olabisi A, Wimalasena K, et al. (2008) Catalytic turnover dependent modification of the Pseudomonas aeruginosa heme oxygenase (pa-HO) by 5,6-O-isopropyledine-2-O-allyl-ascorbic acid. Journal of Inorganic Biochemistry. 102: 251-9
Samms WC, Perera RP, Wimalasena DS, et al. (2007) Perturbation of dopamine metabolism by 3-amino-2-(4'-halophenyl)propenes leads to increased oxidative stress and apoptotic SH-SY5Y cell death. Molecular Pharmacology. 72: 744-52
Wimalasena DS, Wiese TJ, Wimalasena K. (2007) Copper ions disrupt dopamine metabolism via inhibition of V-H+-ATPase: a possible contributing factor to neurotoxicity. Journal of Neurochemistry. 101: 313-26
Olabisi AO, Mahindaratne MP, Wimalasena K. (2005) A convenient entry to C2- and C3-substituted gulono-gamma-lactone derivatives from L-ascorbic acid. The Journal of Organic Chemistry. 70: 6782-9
Bhakta M, Hollenberg PF, Wimalasena K. (2005) Evidence for a hydrogen abstraction mechanism in P450-catalyzed N-dealkylations. Chemical Communications (Cambridge, England). 265-7
Bhakta MN, Hollenberg PF, Wimalasena K. (2005) P(450)/NADPH/O(2)- and P(450)/PhIO-catalyzed N-dealkylations are mechanistically distinct. Journal of the American Chemical Society. 127: 1376-7
Bhakta MN, Wimalasena K. (2005) A Mechanistic Comparison between Cytochrome P450- and Chloroperoxidase-CatalyzedN-Dealkylation ofN,N-Dialkyl Anilines European Journal of Organic Chemistry. 2005: 4801-4805
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