Scott F. Singleton
Affiliations: | Rice University, Houston, TX |
Area:
BiochemistryGoogle:
"Scott Singleton"Mean distance: (not calculated yet)
Children
Sign in to add trainee| Jie Xiao | grad student | 1997-2002 | Rice University (BME Tree) |
| Neil C. Sharma | grad student | 2004 | Rice University |
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Publications
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| Peterson EJ, Kireev D, Moon AF, et al. (2013) Inhibitors of Streptococcus pneumoniae surface endonuclease EndA discovered by high-throughput screening using a PicoGreen fluorescence assay. Journal of Biomolecular Screening. 18: 247-57 |
| Carroll MJ, Mauldin RV, Gromova AV, et al. (2012) Evidence for dynamics in proteins as a mechanism for ligand dissociation. Nature Chemical Biology. 8: 246-52 |
| Peterson EJ, Janzen WP, Kireev D, et al. (2012) High-throughput screening for RecA inhibitors using a transcreener adenosine 5'-O-diphosphate assay. Assay and Drug Development Technologies. 10: 260-8 |
| Carroll MJ, Gromova AV, Miller KR, et al. (2011) Direct detection of structurally resolved dynamics in a multiconformation receptor-ligand complex. Journal of the American Chemical Society. 133: 6422-8 |
| Sexton JZ, Wigle TJ, He Q, et al. (2010) Novel Inhibitors of E. coli RecA ATPase Activity. Current Chemical Genomics. 4: 34-42 |
| Wigle TJ, Sexton JZ, Gromova AV, et al. (2009) Inhibitors of RecA activity discovered by high-throughput screening: cell-permeable small molecules attenuate the SOS response in Escherichia coli. Journal of Biomolecular Screening. 14: 1092-101 |
| Singleton SF, Roca AI, Lee AM, et al. (2007) Probing the structure of RecA-DNA filaments. Advantages of a fluorescent guanine analog. Tetrahedron. 63: 3553-3566 |
| Lee AM, Wigle TJ, Singleton SF. (2007) A complementary pair of rapid molecular screening assays for RecA activities. Analytical Biochemistry. 367: 247-58 |
| Cline DJ, Holt SL, Singleton SF. (2007) Inhibition of Escherichia coli RecA by rationally redesigned N-terminal helix. Organic & Biomolecular Chemistry. 5: 1525-8 |
| Xiao J, Lee AM, Singleton SF. (2006) Direct evaluation of a kinetic model for RecA-mediated DNA-strand exchange: the importance of nucleic acid dynamics and entropy during homologous genetic recombination. Chembiochem : a European Journal of Chemical Biology. 7: 1265-78 |