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Ernst Schonbrunn

Affiliations: 
University of Kansas, Lawrence, KS, United States 
Area:
Biochemistry
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"Ernst Schonbrunn"
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Parents

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Children

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Melanie A. Priestman grad student 2005 University of Kansas
Todd A. Funke grad student 2008 University of Kansas
Huijong Han grad student 2008 University of Kansas

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Publications

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Morozova A, Chan SC, Bayle S, et al. (2023) Development of potent and selective ULK1/2 inhibitors based on 7-azaindole scaffold with favorable in vivo properties. European Journal of Medicinal Chemistry. 266: 116101
Faber EB, Sun L, Tang J, et al. (2023) Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding. Nature Communications. 14: 3213
Lee JC, Hong KH, Becker A, et al. (2021) Tetrahydroindazole inhibitors of CDK2/cyclin complexes. European Journal of Medicinal Chemistry. 214: 113232
Hanna CB, Mudaliar D, John K, et al. (2020) Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis†. Biology of Reproduction
Ycas PD, Zahid H, Chan A, et al. (2020) New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development. Organic & Biomolecular Chemistry
Li Q, Karim RM, Cheng M, et al. (2020) Inhibition of p53 DNA binding by a small molecule protects mice from radiation toxicity. Oncogene
Huang Q, Chen L, Schonbrunn E, et al. (2020) MDMX inhibits casein kinase 1α activity and stimulates Wnt signaling. The Embo Journal. e104410
Olson N, Kroc S, Johnson J, et al. (2020) NMR Analyses of Acetylated H2A.Z Isoforms Identify Differential Binding Interactions with the Bromodomain of the NURF Nucleosome Remodeling Complex. Biochemistry
Durbin AD, Wimalasena V, Zimmerman MW, et al. (2020) Abstract PR11: EP300 controls the oncogenic enhancer landscape of high-risk neuroblastoma Cancer Research. 80
Liu X, Huang Q, Chen L, et al. (2019) Tumor-derived CK1α mutations enhance MDMX inhibition of p53. Oncogene
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