Jeff W. Hill, Ph.D.

Affiliations: 
2001 University of Texas Medical Branch, Galveston, TX 
Area:
Biochemistry, Genetics
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Sankar Mitra grad student 2001 UTMB
 (Repair of 8-oxoguanine by human 8-oxoguanine-DNA glycosylase: Coordination in base excision repair.)
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Publications

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Smith TR, Liu-Mares W, Van Emburgh BO, et al. (2011) Genetic polymorphisms of multiple DNA repair pathways impact age at diagnosis and TP53 mutations in breast cancer. Carcinogenesis. 32: 1354-60
Hill JW, Hu JJ, Evans MK. (2008) OGG1 is degraded by calpain following oxidative stress and cisplatin exposure. Dna Repair. 7: 648-54
Hill JW, Evans MK. (2007) A novel R229Q OGG1 polymorphism results in a thermolabile enzyme that sensitizes KG-1 leukemia cells to DNA damaging agents. Cancer Detection and Prevention. 31: 237-43
Hill JW, Evans MK. (2006) Dimerization and opposite base-dependent catalytic impairment of polymorphic S326C OGG1 glycosylase. Nucleic Acids Research. 34: 1620-32
Mitra S, Izumi T, Boldogh I, et al. (2002) Choreography of oxidative damage repair in mammalian genomes. Free Radical Biology & Medicine. 33: 15-28
Hazra TK, Hill JW, Izumi T, et al. (2001) Multiple DNA glycosylases for repair of 8-oxoguanine and their potential in vivo functions. Progress in Nucleic Acid Research and Molecular Biology. 68: 193-205
Cappelli E, Hazra T, Hill JW, et al. (2001) Rates of base excision repair are not solely dependent on levels of initiating enzymes. Carcinogenesis. 22: 387-93
Hill JW, Hazra TK, Izumi T, et al. (2001) Stimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: potential coordination of the initial steps in base excision repair. Nucleic Acids Research. 29: 430-8
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