Phillip D. Holler, Ph.D.
Affiliations: | 2002 | University of Illinois, Urbana-Champaign, Urbana-Champaign, IL |
Area:
Biochemistry, ImmunologyGoogle:
"Phillip Holler"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| David Michael Kranz | grad student | 2002 | UIUC | |
| (Engineering and characterization of high-affinity T cell receptors.) | ||||
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Publications
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| Chervin AS, Stone JD, Holler PD, et al. (2009) The impact of TCR-binding properties and antigen presentation format on T cell responsiveness. Journal of Immunology (Baltimore, Md. : 1950). 183: 1166-78 |
| Holler PD, Yamagata T, Jiang W, et al. (2007) The same genomic region conditions clonal deletion and clonal deviation to the CD8alphaalpha and regulatory T cell lineages in NOD versus C57BL/6 mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 7187-92 |
| Brophy SE, Jones LL, Holler PD, et al. (2007) Cellular uptake followed by class I MHC presentation of some exogenous peptides contributes to T cell stimulatory capacity. Molecular Immunology. 44: 2184-94 |
| Ge Q, Holler PD, Mahajan VS, et al. (2006) Development of CD4+ T cells expressing a nominally MHC class I-restricted T cell receptor by two different mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 103: 1822-7 |
| Chlewicki LK, Holler PD, Monti BC, et al. (2005) High-affinity, peptide-specific T cell receptors can be generated by mutations in CDR1, CDR2 or CDR3. Journal of Molecular Biology. 346: 223-39 |
| Peng KW, Holler PD, Orr BA, et al. (2004) Targeting virus entry and membrane fusion through specific peptide/MHC complexes using a high-affinity T-cell receptor. Gene Therapy. 11: 1234-9 |
| Holler PD, Kranz DM. (2004) T cell receptors: affinities, cross-reactivities, and a conformer model. Molecular Immunology. 40: 1027-31 |
| Leifert JA, Holler PD, Harkins S, et al. (2003) The cationic region from HIV tat enhances the cell-surface expression of epitope/MHC class I complexes. Gene Therapy. 10: 2067-73 |
| Holler PD, Kranz DM. (2003) Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation. Immunity. 18: 255-64 |
| Brophy SE, Holler PD, Kranz DM. (2003) A yeast display system for engineering functional peptide-MHC complexes. Journal of Immunological Methods. 272: 235-46 |