Lukasz K. Chlewicki, Ph.D.
Affiliations: | 2004 | University of Illinois, Urbana-Champaign, Urbana-Champaign, IL |
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Parents
Sign in to add mentor| David Michael Kranz | grad student | 2004 | UIUC | |
| (Structure, function and engineering of peptide -MHC binding receptors.) | ||||
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Publications
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| Tang H, Wang Y, Chlewicki LK, et al. (2016) Facilitating T Cell Infiltration in Tumor Microenvironment Overcomes Resistance to PD-L1 Blockade. Cancer Cell. 29: 285-296 |
| Zloza A, Lyons GE, Chlewicki LK, et al. (2011) Engagement of NK receptor NKG2D, but not 2B4, results in self-reactive CD8+ T cells and autoimmune vitiligo. Autoimmunity. 44: 599-606 |
| Chlewicki LK, Kumar V. (2010) A model system for studying NK cell receptor signaling. Methods in Molecular Biology (Clifton, N.J.). 612: 177-98 |
| Li Y, Hofmann M, Wang Q, et al. (2009) Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition. Immunity. 31: 35-46 |
| Bowerman NA, Crofts TS, Chlewicki L, et al. (2009) Engineering the binding properties of the T cell receptor:peptide:MHC ternary complex that governs T cell activity. Molecular Immunology. 46: 3000-8 |
| Chlewicki LK, Holler PD, Monti BC, et al. (2005) High-affinity, peptide-specific T cell receptors can be generated by mutations in CDR1, CDR2 or CDR3. Journal of Molecular Biology. 346: 223-39 |
| Dam J, Guan R, Natarajan K, et al. (2003) Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b). Nature Immunology. 4: 1213-22 |
| Holler PD, Chlewicki LK, Kranz DM. (2003) TCRs with high affinity for foreign pMHC show self-reactivity. Nature Immunology. 4: 55-62 |