David H. Aggen, Ph.D.
Affiliations: | 2010 | University of Illinois, Urbana-Champaign, Urbana-Champaign, IL |
Area:
Biochemistry, Immunology, Molecular BiologyGoogle:
"David Aggen"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| David Michael Kranz | grad student | 2010 | UIUC | |
| (Engineering human single-chain T cell receptors.) | ||||
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Publications
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| Dallos M, Aggen DH, Hawley J, et al. (2019) A randomized phase Ib/II study of nivolumab with or without BMS-986253 in combination with a short course of ADT in men with castration-sensitive prostate cancer (MAGIC-8). Journal of Clinical Oncology. 37: TPS329-TPS329 |
| Aggen DH, Ghasemzadeh A, Mao W, et al. (2019) Preclinical development of combination therapy targeting the dominant cytokine interleukin-1β for renal cell carcinoma. Journal of Clinical Oncology. 37: e14237-e14237 |
| Dallos M, Obradovic A, Chowdhury N, et al. (2019) Human prostate cancer immune phenotypes after androgen deprivation therapy. Journal of Clinical Oncology. 37: 5083-5083 |
| Chowdhury N, Obradovic A, Aggen D, et al. (2019) Abstract 1476: Decoding the immunologic landscape of human clear cell renal carcinoma Cancer Research. 79: 1476-1476 |
| Wang* V, Obradovic A, Chowdhury N, et al. (2019) MP21-01 SINGLE CELL TRANSCRIPTIONAL PROFILING OF IMMUNE POPULATIONS WITHIN RENAL CELL CARCINOMA TUMOR MICROENVIRONMENT Journal of Urology. 201 |
| Schmitt TM, Aggen DH, Ishida-Tsubota K, et al. (2017) Generation of higher affinity T cell receptors by antigen-driven differentiation of progenitor T cells in vitro. Nature Biotechnology |
| Stone JD, Harris DT, Soto CM, et al. (2014) A novel T cell receptor single-chain signaling complex mediates antigen-specific T cell activity and tumor control. Cancer Immunology, Immunotherapy : Cii. 63: 1163-76 |
| Schmitt TM, Aggen DH, Stromnes IM, et al. (2013) Enhanced-affinity murine T-cell receptors for tumor/self-antigens can be safe in gene therapy despite surpassing the threshold for thymic selection. Blood. 122: 348-56 |
| Schmitt TM, Greenberg PD, Aggen DH, et al. (2013) Abstract PR12: Early TCRα expression during T cell development for the generation of enhanced-affinity TCRs for TCR gene therapy. Cancer Research. 73 |
| Greenberg PD, Ochsenreither S, Schmitt T, et al. (2013) Abstract IA1: T cells vs. tumor cells: Arming/deploying T cells for a successful battle. Cancer Research. 73 |