Sarah M. Amie, Ph.D.

Affiliations: 
2014 School of Medicine and Dentistry University of Rochester, Rochester, NY 
Area:
Microbiology Biology, Biochemistry, Virology Biology
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Robert A. Bambara grad student 2014 Rochester
 (Replication of HIV in Macrophages: Effects of SAMHD1 on dNTP Levels, Viral Mutagenesis, and Antiviral Efficacy.)
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Publications

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Allouch A, David A, Amie SM, et al. (2014) Reply to Pauls et al.: P21 is a master regulator of HIV replication in macrophages through dNTP synthesis block Proceedings of the National Academy of Sciences of the United States of America. 111: E1325-E1326
Brandariz-Nuñez A, Valle-Casuso JC, White TE, et al. (2013) Contribution of oligomerization to the anti-HIV-1 properties of SAMHD1. Retrovirology. 10: 131
Allouch A, David A, Amie SM, et al. (2013) P21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway Proceedings of the National Academy of Sciences of the United States of America. 110: E3997-E4006
Amie SM, Bambara RA, Kim B. (2013) GTP is the primary activator of the anti-HIV restriction factor SAMHD1. The Journal of Biological Chemistry. 288: 25001-6
Hollenbaugh JA, Gee P, Baker J, et al. (2013) Host factor SAMHD1 restricts DNA viruses in non-dividing myeloid cells. Plos Pathogens. 9: e1003481
Amie SM, Daly MB, Noble E, et al. (2013) Anti-HIV host factor SAMHD1 regulates viral sensitivity to nucleoside reverse transcriptase inhibitors via modulation of cellular deoxyribonucleoside triphosphate (dNTP) levels. The Journal of Biological Chemistry. 288: 20683-91
White TE, Brandariz-Nuñez A, Valle-Casuso JC, et al. (2013) The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation. Cell Host & Microbe. 13: 441-51
Goujon C, Schaller T, Galão RP, et al. (2013) Evidence for IFNα-induced, SAMHD1-independent inhibitors of early HIV-1 infection. Retrovirology. 10: 23
Amie SM, Noble E, Kim B. (2013) Intracellular nucleotide levels and the control of retroviral infections. Virology. 436: 247-54
White TE, Brandariz-Nuñez A, Valle-Casuso JC, et al. (2013) Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1. Virology. 436: 81-90
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