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Can G. Pham, Ph.D.

Affiliations: 
2005 University of Chicago, Chicago, IL 
Area:
Molecular Biology, Cell Biology, Biochemistry
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Guido Franzoso grad student 2005 Chicago
 (Control of apoptosis by NF-kappaB/Rel transcription factors through suppression of reactive oxygen species.)

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Xu J, Pham CG, Albanese SK, et al. (2016) Mechanistically distinct cancer-associated mTOR activation clusters predict sensitivity to rapamycin. The Journal of Clinical Investigation
Liu H, Westergard TD, Cashen A, et al. (2014) Proteasome inhibitors evoke latent tumor suppression programs in pro-B MLL leukemias through MLL-AF4. Cancer Cell. 25: 530-42
Voss MH, Hakimi AA, Chen Y, et al. (2013) Effective monotherapy despite intratumor heterogeneity: Clonal convergence within the PI3K pathway and sensitivity to mTOR inhibitors in patients with advanced renal cell carcinoma (RCC). Journal of Clinical Oncology. 31: 4573-4573
Kuntzen C, Zazzeroni F, Pham CG, et al. (2007) A method for isolating prosurvival targets of NF-kappaB/Rel transcription factors. Methods in Molecular Biology (Clifton, N.J.). 399: 99-124
Pham CG, Bubici C, Zazzeroni F, et al. (2007) Upregulation of Twist-1 by NF-kappaB blocks cytotoxicity induced by chemotherapeutic drugs. Molecular and Cellular Biology. 27: 3920-35
Papa S, Bubici C, Zazzeroni F, et al. (2006) The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease. Cell Death and Differentiation. 13: 712-29
Bubici C, Papa S, Pham CG, et al. (2006) The NF-kappaB-mediated control of ROS and JNK signaling. Histology and Histopathology. 21: 69-80
Pham CG, Papa S, Bubici C, et al. (2005) In the Crosshairs: NF-κB Targets the JNK Signaling Cascade. Current Medicinal Chemistry. Anti-Inflammatory & Anti-Allergy Agents. 4: 569-576
Papa S, Bubici C, Pham CG, et al. (2005) NF-kappaB meets ROS: an 'iron-ic' encounter. Cell Death and Differentiation. 12: 1259-62
Pham CG, Papa S, Bubici C, et al. (2005) Oxygen JNKies: phosphatases overdose on ROS. Developmental Cell. 8: 452-4
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