John E. Dominy, Ph.D.
Affiliations: | 2008 | Cornell University, Ithaca, NY, United States |
Area:
Nutrition, Molecular BiologyGoogle:
"John Dominy"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Martha H. Stipanuk | grad student | 2008 | Cornell | |
| (A story of two mammalian thiol dioxygenases: A characterization of substrate mediated post-translation modifications of cysteine dioxygenase and the discovery of cysteamine dioxygenase.) | ||||
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Publications
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| Tavares CD, Sharabi K, Dominy JE, et al. (2016) The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyl Transferase and the PGC-1α Transcriptional Coactivator. The Journal of Biological Chemistry |
| Chow JD, Lawrence RT, Healy ME, et al. (2014) Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation. Molecular Metabolism. 3: 419-31 |
| Lee Y, Dominy JE, Choi YJ, et al. (2014) Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression. Nature. 510: 547-51 |
| Dominy J, Puigserver P, Cantó C. (2013) In vivo measurement of the acetylation state of sirtuin substrates as a proxy for sirtuin activity. Methods in Molecular Biology (Clifton, N.J.). 1077: 217-37 |
| Hall JA, Dominy JE, Lee Y, et al. (2013) The sirtuin family's role in aging and age-associated pathologies. The Journal of Clinical Investigation. 123: 973-9 |
| Lim JH, Gerhart-Hines Z, Dominy JE, et al. (2013) Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex. The Journal of Biological Chemistry. 288: 7117-26 |
| Dominy JE, Lee Y, Jedrychowski MP, et al. (2012) The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis. Molecular Cell. 48: 900-13 |
| Dominy JE, Vazquez F, Puigserver P. (2012) Glycine decarboxylase cleaves a "malignant" metabolic path to promote tumor initiation. Cancer Cell. 21: 143-5 |
| Dominy JE, Gerhart-Hines Z, Puigserver P. (2011) Nutrient-dependent acetylation controls basic regulatory metabolic switches and cellular reprogramming. Cold Spring Harbor Symposia On Quantitative Biology. 76: 203-9 |
| Gerhart-Hines Z, Dominy JE, Blättler SM, et al. (2011) The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+). Molecular Cell. 44: 851-63 |