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Marc de la Roche, Ph.D.

Affiliations: 
2004 Queen's University, Canada, Kingston, Ontario, Canada 
Area:
Biochemistry
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Graham P. Cote grad student 2004 Queen's University, Canada
 (Regulation of class I and class II myosins in Dictyostelium discoideum.)

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Tovey CA, Tsuji C, Egerton A, et al. (2021) Autoinhibition of Cnn binding to γ-TuRCs prevents ectopic microtubule nucleation and cell division defects. The Journal of Cell Biology. 220
Yang Y, de la Roche M, Crawley SW, et al. (2013) PakB binds to the SH3 domain of Dictyostelium Abp1 and regulates its effects on cell polarity and early development. Molecular Biology of the Cell. 24: 2216-27
Crawley SW, de la Roche MA, Lee SF, et al. (2006) Identification and characterization of an 8-kDa light chain associated with Dictyostelium discoideum MyoB, a class I myosin. The Journal of Biological Chemistry. 281: 6307-15
de la Roche M, Mahasneh A, Lee SF, et al. (2005) Cellular distribution and functions of wild-type and constitutively activated Dictyostelium PakB. Molecular Biology of the Cell. 16: 238-47
De La Roche MA, Lee SF, Côté GP. (2003) The Dictyostelium class I myosin, MyoD, contains a novel light chain that lacks high-affinity calcium-binding sites. The Biochemical Journal. 374: 697-705
De la Roche MA, Smith JL, Betapudi V, et al. (2002) Signaling pathways regulating Dictyostelium myosin II. Journal of Muscle Research and Cell Motility. 23: 703-18
De La Roche MA, Smith JL, Rico M, et al. (2002) Dictyostelium discoideum has a single diacylglycerol kinase gene with similarity to mammalian theta isoforms. The Biochemical Journal. 368: 809-15
de la Roche MA, Côté GP. (2001) Regulation of Dictyostelium myosin I and II. Biochimica Et Biophysica Acta. 1525: 245-61
Lee SF, Mahasneh A, de la Roche M, et al. (1998) Regulation of the p21-activated kinase-related Dictyostelium myosin I heavy chain kinase by autophosphorylation, acidic phospholipids, and Ca2+-calmodulin. The Journal of Biological Chemistry. 273: 27911-7
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