Whitney V. Christian, Ph.D.

Affiliations: 
2013 School of Medicine and Dentistry University of Rochester, Rochester, NY 
Area:
Toxicology
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"Whitney Christian"
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Patricia M. Hinkle grad student 2013 Rochester
 (Identification of Residues Required for Functional Interaction of the Two Subunits of the Organic Solute Transporter, OSTalpha-OSTbeta.)
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Publications

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Christian WV, Hinkle PM. (2017) Global functions of extracellular, transmembrane and cytoplasmic domains of organic solute transporter β subunit. The Biochemical Journal
Ballatori N, Christian WV, Wheeler SG, et al. (2013) The heteromeric organic solute transporter, OSTα-OSTβ/SLC51: a transporter for steroid-derived molecules. Molecular Aspects of Medicine. 34: 683-92
Christian WV, Li N, Hinkle PM, et al. (2012) β-Subunit of the Ostα-Ostβ organic solute transporter is required not only for heterodimerization and trafficking but also for function. The Journal of Biological Chemistry. 287: 21233-43
Fang F, Christian WV, Gorman SG, et al. (2010) Neurosteroid transport by the organic solute transporter OSTα-OSTβ. Journal of Neurochemistry. 115: 220-33
Cui M, Aras R, Christian WV, et al. (2009) The organic cation transporter-3 is a pivotal modulator of neurodegeneration in the nigrostriatal dopaminergic pathway. Proceedings of the National Academy of Sciences of the United States of America. 106: 8043-8
Ballatori N, Li N, Fang F, et al. (2009) OST alpha-OST beta: a key membrane transporter of bile acids and conjugated steroids. Frontiers in Bioscience (Landmark Edition). 14: 2829-44
Ballatori N, Fang F, Christian WV, et al. (2008) Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver. American Journal of Physiology. Gastrointestinal and Liver Physiology. 295: G179-G186
Ballatori N, Christian WV, Lee JY, et al. (2005) OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia. Hepatology (Baltimore, Md.). 42: 1270-9
Dawson PA, Hubbert M, Haywood J, et al. (2005) The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter. The Journal of Biological Chemistry. 280: 6960-8
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