Louis B. Hersh

Affiliations: 
University of Kentucky, Lexington, KY 
Area:
Biochemistry
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"Louis Hersh"
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Publications

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Song ES, Rodgers DW, Hersh LB. (2018) Insulin-degrading enzyme is not secreted from cultured cells. Scientific Reports. 8: 2335
Song ES, Jang H, Guo HF, et al. (2017) Inositol phosphates and phosphoinositides activate insulin-degrading enzyme, while phosphoinositides also mediate binding to endosomes. Proceedings of the National Academy of Sciences of the United States of America
Verma N, Ly H, Liu M, et al. (2016) Intraneuronal Amylin Deposition Peroxidative Membrane Injury and Increased IL-1β Synthesis in Brains of Alzheimer's Disease Patients with Type-2 Diabetes and in Diabetic HIP Rats. Journal of Alzheimer's Disease : Jad
Guan H, Chow KM, Song E, et al. (2015) The Mitochondrial Peptidase Pitrilysin Degrades Islet Amyloid Polypeptide in Beta-Cells. Plos One. 10: e0133263
Song ES, Ozbil M, Zhang T, et al. (2015) An Extended Polyanion Activation Surface in Insulin Degrading Enzyme. Plos One. 10: e0133114
Chin-Chan M, Segovia J, Quintanar L, et al. (2015) Mercury Reduces the Enzymatic Activity of Neprilysin in Differentiated SH-SY5Y Cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 145: 128-37
Guan H, Chow KM, Song E, et al. (2015) The mitochondrial peptidase pitrilysin degrades islet amyloid polypeptide in beta-cells Plos One. 10
Song ES, Melikishvili M, Fried MG, et al. (2012) Cysteine 904 is required for maximal insulin degrading enzyme activity and polyanion activation. Plos One. 7: e46790
Guan H, Chow KM, Shah R, et al. (2012) Degradation of islet amyloid polypeptide by neprilysin. Diabetologia. 55: 2989-98
Sexton T, Hitchcook LJ, Rodgers DW, et al. (2012) Active site mutations change the cleavage specificity of neprilysin. Plos One. 7: e32343
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