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Mary Kay H. Pflum

Affiliations: 
2001- Chemistry Wayne State University, Detroit, MI, United States 
Area:
Biochemistry, Cell Biology
Website:
https://clasprofiles.wayne.edu/profile/aj9044
Google:
"Mary Kay Hamm Pflum"
Bio:

http://chem.wayne.edu/pflumgroup/MKPBioforWebpage.html

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Parents

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Jerry R. Mohrig research assistant 1992 Carleton College
Alanna Schepartz grad student 1999 Yale
 (BZIP proteins and their accessory factors : DNA binding and transcription activation.)
Stuart L. Schreiber post-doc 2001 Harvard

Children

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Paulina Karwowska-Desaulniers grad student 2007 Wayne State
Agnes M. W. V. Arachchige Dona grad student 2007 Wayne State
Anton V. Bieliauskas grad student 2008 Wayne State
Keith D. Green grad student 2008 Wayne State
Sujit Suwal grad student 2009 Wayne State
Sujith V. Weerasinghe grad student 2009 Wayne State
Emily L. Aubie grad student 2011 Wayne State
Satish K. Garre Venkata Raghavendra grad student 2013 Wayne State
Kona A. Senevirathne grad student 2013 Wayne State
Magdalene K. Wambua grad student 2013 Wayne State

Collaborators

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Publications

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Karaj E, Sindi SH, Kuganesan N, et al. (2022) First-in-Class Dual Mechanism Ferroptosis-HDAC Inhibitor Hybrids. Journal of Medicinal Chemistry
Tillekeratne LMV, Al-Hamashi AA, Dlamini S, et al. (2019) In Search of Selectivity: Design, Synthesis, and Biological Evaluation of New Classes of HDAC Inhibitors Proceedings. 22: 63
Nalawansha DA, Gomes ID, Wambua MK, et al. (2017) HDAC Inhibitor-Induced Mitotic Arrest Is Mediated by Eg5/KIF11 Acetylation. Cell Chemical Biology
Negmeldin AT, Padige G, Bieliauskas AV, et al. (2017) Structural Requirements of HDAC Inhibitors: SAHA Analogues Modified at the C2 Position Display HDAC6/8 Selectivity. Acs Medicinal Chemistry Letters. 8: 281-286
Nalawansha DA, Pflum MK. (2017) LSD1 Substrate Binding and Gene Expression Are Affected by HDAC1-Mediated Deacetylation. Acs Chemical Biology. 12: 254-264
Embogama DM, Pflum MK. (2017) K-BILDS: A Kinase Substrate Discovery Tool. Chembiochem : a European Journal of Chemical Biology. 18: 136-141
Almaliti J, Al-Hamashi AA, Negmeldin AT, et al. (2016) Largazole Analogues Embodying Radical Changes in the Depsipeptide Ring: Development of a More Selective and Highly Potent Analogue. Journal of Medicinal Chemistry
Dedigama-Arachchige PM, Pflum MK. (2016) K-CLASP: A Tool to Identify Phosphosite Specific Kinases and Interacting Proteins. Acs Chemical Biology. 11: 3251-3255
Bieliauskas AV, Weerasinghe SV, Negmeldin AT, et al. (2016) Structural Requirements of Histone Deacetylase Inhibitors: SAHA Analogs Modified on the Hydroxamic Acid. Archiv Der Pharmazie
Senevirathne C, Embogama DM, Anthony TA, et al. (2016) The generality of kinase-catalyzed biotinylation. Bioorganic & Medicinal Chemistry. 24: 12-9
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