Ralph M. Pollack

Affiliations: 
Biochemistry University of Maryland, Baltimore County, Baltimore, MD, United States 
Area:
Biochemistry, Pharmacology
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"Ralph Pollack"
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Children

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Xudong Yao grad student 2000 UMBC
Thomas C. Wilde grad student 2005 UMBC
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Publications

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Wilde TC, Blotny G, Pollack RM. (2008) Experimental evidence for enzyme-enhanced coupled motion/quantum mechanical hydrogen tunneling by ketosteroid isomerase. Journal of the American Chemical Society. 130: 6577-85
Houck WJ, Pollack RM. (2004) Temperature effects on the catalytic activity of the D38E mutant of 3-oxo-Delta5-steroid isomerase: favorable enthalpies and entropies of activation relative to the nonenzymatic reaction catalyzed by acetate ion. Journal of the American Chemical Society. 126: 16416-25
Pollack RM. (2004) Enzymatic mechanisms for catalysis of enolization: ketosteroid isomerase. Bioorganic Chemistry. 32: 341-53
Houck WJ, Pollack RM. (2003) Activation enthalpies and entropies for the microscopic rate constants of acetate-catalyzed isomerization of 5-androstene-3,17-dione. Journal of the American Chemical Society. 125: 10206-12
Thornburg LD, Goldfeder YR, Wilde TC, et al. (2001) Selective catalysis of elementary steps by Asp-99 and Tyr-14 of 3-Oxo-delta(5)-steroid isomerase. Journal of the American Chemical Society. 123: 9912-3
Hénot F, Pollack RM. (2000) Catalytic activity of the D38A mutant of 3-oxo-Delta 5-steroid isomerase: recruitment of aspartate-99 as the base. Biochemistry. 39: 3351-9
Petrounia IP, Blotny G, Pollack RM. (2000) Binding of 2-naphthols to D38E mutants of 3-oxo-Delta 5-steroid isomerase: variation of ligand ionization state with the nature of the electrophilic component. Biochemistry. 39: 110-6
Pollack RM, Thornburg LD, Wu ZR, et al. (1999) Mechanistic insights from the three-dimensional structure of 3-oxo-Delta(5)-steroid isomerase. Archives of Biochemistry and Biophysics. 370: 9-15
Yao X, Pollack RM. (1999) Electronic effects on enol acidity and keto-enol equilibrium constants for ring-substituted 2-tetralones Canadian Journal of Chemistry. 77: 634-638
Yao X, Gold MA, Pollack RM. (1999) Transition State Imbalance in Proton Transfer from Phenyl Ring-Substituted 2-Tetralones to Acetate Ion Journal of the American Chemical Society. 121: 6220-6225
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