Michael D. Feldkamp, Ph.D.

Affiliations: 
2010 Biochemistry University of Iowa, Iowa City, IA 
Area:
General Biophysics
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Parents

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Madeline A. Shea grad student 2010 University of Iowa
 (Thermodynamic and structural determinants of calcium-independent interactions of calmodulin.)

Collaborators

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Lokesh Gakhar collaborator
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Publications

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Hovey L, Fowler CA, Mahling R, et al. (2017) Calcium triggers reversal of calmodulin on nested anti-parallel sites in the IQ motif of the neuronal voltage-dependent sodium channel NaV1.2. Biophysical Chemistry. 224: 1-19
Feldkamp MD, Gakhar L, Pandey N, et al. (2015) Opposing orientations of the anti-psychotic drug trifluoperazine selected by alternate conformations of M144 in calmodulin. Proteins. 83: 989-96
Frank AO, Vangamudi B, Feldkamp MD, et al. (2014) Discovery of a potent stapled helix peptide that binds to the 70N domain of replication protein A. Journal of Medicinal Chemistry. 57: 2455-61
Miller MS, Fowler A, Feldkamp MD, et al. (2014) Calcium-Mediated Reversal of CaM on the Nav 1.2 IQ Motif: Nested Anti-Parallel Sites Biophysical Journal. 106: 48a
Marx DC, Miller MS, Hovey L, et al. (2014) Specificity of Calmodulin Recognition of Human Voltage-Gated Sodium Channels Biophysical Journal. 106: 326a
Damo SM, Feldkamp MD, Chagot B, et al. (2013) NMR studies of the interaction of calmodulin with IQ motif peptides. Methods in Molecular Biology (Clifton, N.J.). 963: 173-86
Marx DC, Kim EH, Miller MS, et al. (2013) Two Classes of Calmodulin Binding to IQ Motifs of Voltage-Gated Sodium Channels Biophysical Journal. 104: 100a
Shea MA, Miller MS, Yoder JB, et al. (2013) Calcium-Mediated Tailspin of Calmodulin on the IQ Motif of the Neuronal Voltage-Dependent Sodium Channel Nav1.2 Biophysical Journal. 104: 14a
Shea MA, Miller MS, Yoder JB, et al. (2012) Calmodulin Discrimination Between Voltage-Dependent Sodium Channel IQ Motifs Biophysical Journal. 102: 325a
Feldkamp MD, Yu L, Shea MA. (2011) Structural and energetic determinants of apo calmodulin binding to the IQ motif of the Na(V)1.2 voltage-dependent sodium channel. Structure (London, England : 1993). 19: 733-47
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