Hanjun Guan, Ph.D.
Affiliations: | 2007 | University of Kentucky, Lexington, KY |
Area:
Biochemistry, Neuroscience BiologyGoogle:
"Hanjun Guan"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Louis B. Hersh | grad student | 2007 | University of Kentucky | |
| (The uses of peptidases as a therapeutical approach for Alzheimer's disease.) | ||||
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Publications
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| Guan H, Chow KM, Song E, et al. (2015) The Mitochondrial Peptidase Pitrilysin Degrades Islet Amyloid Polypeptide in Beta-Cells. Plos One. 10: e0133263 |
| Guan H, Chow KM, Song E, et al. (2015) The mitochondrial peptidase pitrilysin degrades islet amyloid polypeptide in beta-cells Plos One. 10 |
| Guan H, Chow KM, Shah R, et al. (2012) Degradation of islet amyloid polypeptide by neprilysin. Diabetologia. 55: 2989-98 |
| Chow KM, Guan H, Hersh LB. (2010) Aminopeptidases do not directly degrade tau protein. Molecular Neurodegeneration. 5: 48 |
| Liu Y, Studzinski C, Beckett T, et al. (2009) Expression of neprilysin in skeletal muscle reduces amyloid burden in a transgenic mouse model of Alzheimer disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1381-6 |
| Guan H, Liu Y, Daily A, et al. (2009) Peripherally expressed neprilysin reduces brain amyloid burden: a novel approach for treating Alzheimer's disease. Journal of Neuroscience Research. 87: 1462-73 |
| Horiguchi A, Chen DY, Goodman OB, et al. (2008) Neutral endopeptidase inhibits prostate cancer tumorigenesis by reducing FGF-2-mediated angiogenesis. Prostate Cancer and Prostatic Diseases. 11: 79-87 |
| Liu Y, Guan H, Klein RL, et al. (2008) P2-343: Peripherally overexpessed neprilysin in muscle reduces brain amyloid in a transgenic mouse model of AD Alzheimer's & Dementia. 4: T473-T473 |
| Liu Y, Guan H, Beckett TL, et al. (2007) In vitro and in vivo degradation of Abeta peptide by peptidases coupled to erythrocytes. Peptides. 28: 2348-55 |
| Horiguchi A, Zheng R, Goodman OB, et al. (2007) Lentiviral vector neutral endopeptidase gene transfer suppresses prostate cancer tumor growth. Cancer Gene Therapy. 14: 583-9 |