Stephen K. Austin, Ph.D.

Affiliations: 
2012 Biology & Biomedical Sciences (Immunology) Washington University, Saint Louis, St. Louis, MO 
Area:
Immunology, Virology Biology, General Biophysics
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Daved H. Fremont grad student 2012 Washington University
 (A Structural Perspective of Antibody Neutralization of Dengue Virus.)
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Publications

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Kim AS, Austin SK, Gardner CL, et al. (2018) Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein. Nature Microbiology
Long F, Fong RH, Austin SK, et al. (2015) Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity. Proceedings of the National Academy of Sciences of the United States of America
Smith SA, Silva LA, Fox JM, et al. (2015) Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus. Cell Host & Microbe. 18: 86-95
Zhang X, Sheng J, Austin SK, et al. (2015) Structure of acidic pH dengue virus showing the fusogenic glycoprotein trimers. Journal of Virology. 89: 743-50
Edeling MA, Austin SK, Shrestha B, et al. (2014) Potent dengue virus neutralization by a therapeutic antibody with low monovalent affinity requires bivalent engagement. Plos Pathogens. 10: e1004072
Austin SK, Dowd KA. (2014) B cell response and mechanisms of antibody protection to West Nile virus. Viruses. 6: 1015-36
Smith SA, de Alwis AR, Kose N, et al. (2013) The potent and broadly neutralizing human dengue virus-specific monoclonal antibody 1C19 reveals a unique cross-reactive epitope on the bc loop of domain II of the envelope protein. Mbio. 4: e00873-13
Lee PD, Mukherjee S, Edeling MA, et al. (2013) The Fc region of an antibody impacts the neutralization of West Nile viruses in different maturation states. Journal of Virology. 87: 13729-40
Sukupolvi-Petty S, Brien JD, Austin SK, et al. (2013) Functional analysis of antibodies against dengue virus type 4 reveals strain-dependent epitope exposure that impacts neutralization and protection. Journal of Virology. 87: 8826-42
Zhou Y, Austin SK, Fremont DH, et al. (2013) The mechanism of differential neutralization of dengue serotype 3 strains by monoclonal antibody 8A1 Virology. 439: 57-64
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