Zhong Dong, Ph.D.

Affiliations: 
2000 Wayne State University, Detroit, MI, United States 
Area:
Pathology, Oncology
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"Zhong Dong"
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Rafael Fridman grad student 2000 Wayne State
 (Role of prostate tumor -stromal interactions in regulation of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs).)
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Publications

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Dong Z, Saliganan AD, Meng H, et al. (2008) Prostate cancer cell-derived urokinase-type plasminogen activator contributes to intraosseous tumor growth and bone turnover. Neoplasia (New York, N.Y.). 10: 439-49
Chinni SR, Yamamoto H, Dong Z, et al. (2008) CXCL12/CXCR4 transactivates HER2 in lipid rafts of prostate cancer cells and promotes growth of metastatic deposits in bone. Molecular Cancer Research : McR. 6: 446-57
Nabha SM, dos Santos EB, Yamamoto HA, et al. (2008) Bone marrow stromal cells enhance prostate cancer cell invasion through type I collagen in an MMP-12 dependent manner. International Journal of Cancer. Journal International Du Cancer. 122: 2482-90
Wiesner C, Nabha S, Burck Dos Santos E, et al. (2008) IMMUNOLOCALIZATION OF SCF AND C-KIT IN BENIGN AND MALIGNANT PROSTATIC TISSUE European Urology Supplements. 7: 174
Bonfil RD, Dong Z, Trindade Filho JC, et al. (2007) Prostate cancer-associated membrane type 1-matrix metalloproteinase: A pivotal role in bone response and intraosseous tumor growth American Journal of Pathology. 170: 2100-2111
Wiesner C, Bonfil RD, Dong Z, et al. (2007) Heterogeneous activation of MMP-9 due to prostate cancer-bone interaction. Urology. 69: 795-9
Yamamoto H, Bonfil RD, Wiesner C, et al. (2007) Quantitative assessment of small intraosseous prostate cancer burden in SCID mice using fluorescence imaging. The Prostate. 67: 107-14
Chinni SR, Yamamoto H, Dong Z, et al. (2007) 664: CXCL12/CXCR4 Trans-Activation of HER2 in Lipid Rafts of Prostate Cancer Cell Membranes Promotes Bone Metastasis The Journal of Urology. 177: 223-223
Nabha SM, Bonfil RD, Yamamoto HA, et al. (2006) Host matrix metalloproteinase-9 contributes to tumor vascularization without affecting tumor growth in a model of prostate cancer bone metastasis. Clinical & Experimental Metastasis. 23: 335-44
Deng X, Bhagat S, Dong Z, et al. (2006) Tissue inhibitor of metalloproteinase-3 induces apoptosis in prostate cancer cells and confers increased sensitivity to paclitaxel. European Journal of Cancer (Oxford, England : 1990). 42: 3267-73
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