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Paul J. Shughrue

Affiliations: 
Merck Pharmaceuticals, Lincoln, NJ, United States 
Area:
estrogen
Google:
"Paul Shughrue"
Mean distance: 17.44 (cluster 7)
 		SNBCP
Cross-listing: Neurotree

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Daniel M. Dorsa post-doc 1991-1995 University of Washington (Neurotree)

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Publications

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Prokai L, Nguyen V, Szarka S, et al. (2015) The prodrug DHED selectively delivers 17β-estradiol to the brain for treating estrogen-responsive disorders. Science Translational Medicine. 7: 297ra113
Dubal DB, Rau SW, Shughrue PJ, et al. (2006) Differential modulation of estrogen receptors (ERs) in ischemic brain injury: a role for ERalpha in estradiol-mediated protection against delayed cell death. Endocrinology. 147: 3076-84
Austin CP, Ky B, Ma L, et al. (2004) Expression of Disrupted-In-Schizophrenia-1, a schizophrenia-associated gene, is prominent in the mouse hippocampus throughout brain development. Neuroscience. 124: 3-10
Merchenthaler I, Dellovade TL, Shughrue PJ. (2003) Neuroprotection by estrogen in animal models of global and focal ischemia. Annals of the New York Academy of Sciences. 1007: 89-100
Shughrue PJ, Ky B, Austin CP. (2003) Localization of B1 bradykinin receptor mRNA in the primate brain and spinal cord: an in situ hybridization study. The Journal of Comparative Neurology. 465: 372-84
Flores CA, Shughrue P, Petersen SL, et al. (2003) Sex-related differences in the distribution of opioid receptor-like 1 receptor mRNA and colocalization with estrogen receptor mRNA in neurons of the spinal trigeminal nucleus caudalis in the rat Neuroscience. 118: 769-778
Shughrue PJ, Dellovade TL, Merchenthaler I. (2002) Estrogen modulates oxytocin gene expression in regions of the rat supraoptic and paraventricular nuclei that contain estrogen receptor-beta. Progress in Brain Research. 139: 15-29
Shughrue PJ, Askew GR, Dellovade TL, et al. (2002) Estrogen-binding sites and their functional capacity in estrogen receptor double knockout mouse brain. Endocrinology. 143: 1643-50
Wilson ME, Rosewell KL, Kashon ML, et al. (2002) Age differentially influences estrogen receptor-alpha (ERalpha) and estrogen receptor-beta (ERbeta) gene expression in specific regions of the rat brain. Mechanisms of Ageing and Development. 123: 593-601
Hrabovszky E, Steinhauser AR, Baraba S K, et al. (2001) Estrogen Receptor-β Immunoreactivity in Luteinizing Hormone-Releasing Hormone Neurons of the Rat Brain. Endocrinology. 142: 3261-3264
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