Thomas D. Christian, Ph.D.
Affiliations: | 2009 | Chemistry | Wayne State University, Detroit, MI, United States |
Area:
BiochemistryGoogle:
"Thomas Christian"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Louis James Romano | grad student | 2009 | Wayne State | |
| (Ensemble and single molecule fluorescence resonance energy transfer investigations into the mechanism of Escherichia coli DNA polymerase I and its role in lesion bypass.) | ||||
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Publications
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| Antonopoulos IH, Xia S, Christian TD, et al. (2016) Large α-helical movements observed in ternary crystals of RB69 DNA polymerase following nucleotide incorporation Journal of Raman Spectroscopy. 47: 110-115 |
| Xia S, Christian TD, Wang J, et al. (2012) Probing minor groove hydrogen bonding interactions between RB69 DNA polymerase and DNA. Biochemistry. 51: 4343-53 |
| Reha-Krantz LJ, Hariharan C, Subuddhi U, et al. (2011) Structure of the 2-aminopurine-cytosine base pair formed in the polymerase active site of the RB69 Y567A-DNA polymerase. Biochemistry. 50: 10136-49 |
| Xia S, Wang M, Lee HR, et al. (2011) Variation in mutation rates caused by RB69pol fidelity mutants can be rationalized on the basis of their kinetic behavior and crystal structures. Journal of Molecular Biology. 406: 558-70 |
| Christian TD, Romano LJ, Rueda D. (2009) Single-molecule measurements of synthesis by DNA polymerase with base-pair resolution. Proceedings of the National Academy of Sciences of the United States of America. 106: 21109-14 |
| Christian TD, Romano LJ. (2009) Monitoring the conformation of benzo[a]pyrene adducts in the polymerase active site using fluorescence resonance energy transfer. Biochemistry. 48: 5382-8 |