Maria L. Parnas, Ph.D.

Affiliations: 
2007 The University of North Dakota, Grand Forks, ND, United States 
Area:
Biochemistry, Neuroscience Biology
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Roxanne A. Vaughan grad student 2007 University of North Dakota
 (Exploring the ligand binding site on the dopamine transporter by photoaffinity labeling and site-directed mutagenesis.)
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Publications

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Tolan NV, Parnas ML, Baudhuin LM, et al. (2015) "Big Data" in Laboratory Medicine. Clinical Chemistry
Parnas ML, Vaughan R. (2011) DAT, dopamine transporter Xpharm: the Comprehensive Pharmacology Reference. 1-10
Parnas ML, Gaffaney JD, Zou MF, et al. (2008) Labeling of dopamine transporter transmembrane domain 1 with the tropane ligand N-[4-(4-azido-3-[125I]iodophenyl)butyl]-2beta-carbomethoxy-3beta-(4-chlorophenyl)tropane implicates proximity of cocaine and substrate active sites. Molecular Pharmacology. 73: 1141-50
Vaughan RA, Sakrikar DS, Parnas ML, et al. (2007) Localization of cocaine analog [125I]RTI 82 irreversible binding to transmembrane domain 6 of the dopamine transporter. The Journal of Biological Chemistry. 282: 8915-25
Newman AH, Cha JH, Cao J, et al. (2006) Design and synthesis of a novel photoaffinity ligand for the dopamine and serotonin transporters based on 2beta-carbomethoxy-3beta-biphenyltropane. Journal of Medicinal Chemistry. 49: 6621-5
Henry LK, Field JR, Adkins EM, et al. (2006) Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants. The Journal of Biological Chemistry. 281: 2012-23
Lever JR, Zou MF, Parnas ML, et al. (2005) Radioiodinated azide and isothiocyanate derivatives of cocaine for irreversible labeling of dopamine transporters: synthesis and covalent binding studies. Bioconjugate Chemistry. 16: 644-9
Vaughan RA, Parnas ML, Gaffaney JD, et al. (2005) Affinity labeling the dopamine transporter ligand binding site. Journal of Neuroscience Methods. 143: 33-40
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