Amy E. Moritz, Ph.D.

Affiliations: 
2011 The University of North Dakota, Grand Forks, ND, United States 
Area:
Biochemistry
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Parents

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Roxanne A. Vaughan grad student 2011 University of North Dakota
 (Post-translational regulation of the dopamine transporter.)
David R. Sibley post-doc NIH (Neurotree)
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Publications

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Sánchez-Soto M, Boldizsar NM, Schardien KA, et al. (2023) G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation. Biomolecules. 13
Sibley DR, Nilson AN, Moritz AE, et al. (2023) Dopamine receptor divergence revealed using a common ligand. Trends in Pharmacological Sciences
Enriquez-Traba J, Yarur-Castillo HE, Flores RJ, et al. (2023) Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors. Biorxiv : the Preprint Server For Biology
Mayer FP, Stewart A, Varman DR, et al. (2023) Kappa Opioid Receptor Antagonism Rescues Genetic Perturbation of Dopamine Homeostasis: Molecular, Physiological and Behavioral Consequences. Biorxiv : the Preprint Server For Biology
Moritz AE, Madaras NS, Rankin ML, et al. (2023) Delineation of G Protein-Coupled Receptor Kinase Phosphorylation Sites within the D Dopamine Receptor and Their Roles in Modulating β-Arrestin Binding and Activation. International Journal of Molecular Sciences. 24
Moritz AE, Bonifazi A, Guerrero AM, et al. (2020) Evidence for a stereoselective mechanism for bitopic activity by extended-length antagonists of the D3 dopamine receptor. Acs Chemical Neuroscience
Moritz AE, Free RB, Weiner WS, et al. (2020) Discovery, Optimization and Characterization of ML417: A Novel and Highly Selective D3 Dopamine Receptor Agonist. Journal of Medicinal Chemistry
Sanchez-Soto M, Verma RK, Willette BKA, et al. (2020) A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity. Science Signaling. 13
Akano EO, Casazza JA, Dranchak P, et al. (2020) Development of a dopaminergic neurodegeneration assay using laser cytometry of Caenorhabditis elegans models of Parkinson’s disease The Faseb Journal. 34: 1-1
Moritz AE, Inbody LR, Gandhi DM, et al. (2020) Structure‐Activity Relationships of a Negative Allosteric Modulator of the D3 Dopamine Receptor and Investigation of its Binding Site The Faseb Journal. 34: 1-1
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