Charles E. Schiaffo, Ph.D.

Affiliations: 
2011 Chemistry The University of Nebraska - Lincoln, Lincoln, NE 
Area:
Organic Chemistry, Biochemistry
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"Charles Schiaffo"
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Patrick H. Dussault grad student 2011 University of Nebraska - Lincoln
 (I. An Improved Procedure for Alkene Ozonolysis. II. Exploring a New Structural Paradigm for Peroxide Antimalarials.)
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Publications

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Sittiwong W, Richardson MW, Schiaffo CE, et al. (2013) Re2O7-catalyzed reaction of hemiacetals and aldehydes with O-, S-, and C-nucleophiles. Beilstein Journal of Organic Chemistry. 9: 1526-32
Ingram K, Schiaffo CE, Sittiwong W, et al. (2012) In vitro and in vivo activity of 3-alkoxy-1,2-dioxolanes against Schistosoma mansoni. The Journal of Antimicrobial Chemotherapy. 67: 1979-86
Schiaffo CE, Rottman M, Wittlin S, et al. (2011) 3-Alkoxy-1,2-Dioxolanes: Synthesis and Evaluation as Potential Antimalarial Agents. Acs Medicinal Chemistry Letters. 2: 316-319
Jiang J, Schiaffo CE, Schwartz CP, et al. (2010) Efficient synthesis and conformational investigations of cis-pentacenediols Tetrahedron Letters. 51: 5732-5735
Wang X, Creek DJ, Schiaffo CE, et al. (2009) Spiroadamantyl 1,2,4-trioxolane, 1,2,4-trioxane, and 1,2,4-trioxepane pairs: relationship between peroxide bond iron(II) reactivity, heme alkylation efficiency, and antimalarial activity. Bioorganic & Medicinal Chemistry Letters. 19: 4542-5
Schiaffo CE, Dussault PH. (2008) Ozonolysis in solvent/water mixtures: direct conversion of alkenes to aldehydes and ketones. The Journal of Organic Chemistry. 73: 4688-90
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