Inge R. Boulet, Ph.D.

Affiliations: 
2007 Universiteit Antwerpen (Belgium) 
Area:
Biochemistry
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Adam L. Raes grad student 2007 Universiteit Antwerpen (Belgium)
 (Structure and function analysis of the KCNQ1 channel in relation to the LQT1 syndrome.)
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Publications

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Heijman J, Spätjens RL, Seyen SR, et al. (2012) Dominant-negative control of cAMP-dependent IKs upregulation in human long-QT syndrome type 1. Circulation Research. 110: 211-9
Labro AJ, Boulet IR, Choveau FS, et al. (2011) The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure. The Journal of Biological Chemistry. 286: 717-25
Labro AJ, Boulet IR, Timmermans JP, et al. (2010) The rate-dependent biophysical properties of the LQT1 H258R mutant are counteracted by a dominant negative effect on channel trafficking. Journal of Molecular and Cellular Cardiology. 48: 1096-104
Labro AJ, Boulet IR, Raes AL, et al. (2010) Substitution Scan of the S4-S5 Linker Region in KCNQ1 Channel: Structural Scaffold for Critical Protein Interactions Biophysical Journal. 98: 120a-121a
Labro AJ, Boulet IR, Mayeur E, et al. (2010) The LQT1 Phenotype of the KCNQ1 H258R Mutant is Unmasked by Faster Stimulation Rates Biophysical Journal. 98: 338a
Boulet IR, Labro AJ, Raes AL, et al. (2007) Role of the S6 C-terminus in KCNQ1 channel gating. The Journal of Physiology. 585: 325-37
Boulet IR, Raes AL, Ottschytsch N, et al. (2006) Functional effects of a KCNQ1 mutation associated with the long QT syndrome. Cardiovascular Research. 70: 466-74
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