Aishwarya Prakash, Ph.D.

Affiliations: 
2010 University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Biochemistry
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"Aishwarya Prakash"
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Parents

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Gloria Borgstahl grad student 2010 University of Nebraska Medical Center
 (Binding studies of human single -stranded DNA binding and repair proteins: Replication protein A and RAD52.)
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Publications

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Koczor CA, Thompson MK, Sharma N, et al. (2023) Polβ/XRCC1 heterodimerization dictates DNA damage recognition and basal Polβ protein levels without interfering with mouse viability or fertility. Dna Repair. 123: 103452
Sharma N, Thompson MK, Arrington JF, et al. (2022) Novel interaction interfaces mediate the interaction between the NEIL1 DNA glycosylase and mitochondrial transcription factor A. Frontiers in Cell and Developmental Biology. 10: 893806
Thompson MK, Sobol RW, Prakash A. (2021) Exploiting DNA Endonucleases to Advance Mechanisms of DNA Repair. Biology. 10
Sharma N, Pasala MS, Prakash A. (2019) Mitochondrial DNA: Epigenetics and Environment. Environmental and Molecular Mutagenesis
Fang Q, Andrews J, Sharma N, et al. (2019) Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress. Nucleic Acids Research. 47: 6269-6286
Sharma N, Chakravarthy S, Longley MJ, et al. (2018) The C-terminal tail of the NEIL1 DNA glycosylase interacts with the human mitochondrial single-stranded DNA binding protein. Dna Repair. 65: 11-19
Blount J, Prakash A. (2018) The changing landscape of Lynch syndrome due to PMS2 mutations. Clinical Genetics. 94: 61-69
Galick HA, Marsden CG, Kathe S, et al. (2017) The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation. Oncotarget. 8: 85883-85895
Prakash A, Moharana K, Wallace SS, et al. (2016) Destabilization of the PCNA trimer mediated by its interaction with the NEIL1 DNA glycosylase. Nucleic Acids Research
Saki M, Prakash A. (2016) DNA Damage Related Crosstalk Between the Nucleus and Mitochondria. Free Radical Biology & Medicine
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