Matthew D. Lynx, Ph.D.

Affiliations: 
2007 University of Notre Dame, Notre Dame, IN, United States 
Area:
Toxicology, Cell Biology, Biochemistry
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Edward E. McKee grad student 2007 Notre Dame
 (An investigation into 3'-azido-3'-deoxythymidine toxicity: Inhibition of thymidine phosphorylation.)
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Publications

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Lynx MD, LaClair DD, McKee EE. (2009) Effects of zidovudine and stavudine on mitochondrial DNA of differentiating 3T3-F442a cells are not associated with imbalanced deoxynucleotide pools. Antimicrobial Agents and Chemotherapy. 53: 1252-5
Lynx MD, Kang BK, McKee EE. (2008) Effect of AZT on thymidine phosphorylation in cultured H9c2, U-937, and Raji cell lines. Biochemical Pharmacology. 75: 1610-5
Susan-Resiga D, Bentley AT, Lynx MD, et al. (2007) Zidovudine inhibits thymidine phosphorylation in the isolated perfused rat heart. Antimicrobial Agents and Chemotherapy. 51: 1142-9
Lynx MD, McKee EE. (2006) 3'-Azido-3'-deoxythymidine (AZT) is a competitive inhibitor of thymidine phosphorylation in isolated rat heart and liver mitochondria. Biochemical Pharmacology. 72: 239-43
Lynx MD, Bentley AT, McKee EE. (2006) 3'-Azido-3'-deoxythymidine (AZT) inhibits thymidine phosphorylation in isolated rat liver mitochondria: a possible mechanism of AZT hepatotoxicity. Biochemical Pharmacology. 71: 1342-8
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