Nikhil M. Urs, Ph.D.
Affiliations: | 2007 | Georgia Institute of Technology, Atlanta, GA |
Area:
Cell Biology, PharmacologyGoogle:
"Nikhil Urs"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Harish Radhakrishna | grad student | 2007 | Georgia Tech | |
| (The regulation of cellular trafficking of the human lysophosphatidic acid receptor 1: Identification of the molecular determinants required for receptor trafficking.) | ||||
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Publications
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| Li H, Urs NM, Horenstein N. (2023) Computational insights into ligand-induced G protein and β-arrestin signaling of the dopamine D1 receptor. Journal of Computer-Aided Molecular Design |
| Li H, Mirabel R, Zimmerman J, et al. (2022) Structure-Functional Selectivity Relationship Studies on A-86929 Analogs and Small Aryl Fragments toward the Discovery of Biased Dopamine D1 Receptor Agonists. Acs Chemical Neuroscience. 13: 1818-1831 |
| Park H, Urs AN, Zimmerman J, et al. (2020) Structure-Functional-Selectivity Relationship Studies of Novel Apomorphine Analogs to Develop D1R/D2R Biased Ligands. Acs Medicinal Chemistry Letters. 11: 385-392 |
| Li YC, Panikker P, Xing B, et al. (2019) Deletion of Glycogen Synthase Kinase-3β in D Receptor-Positive Neurons Ameliorates Cognitive Impairment via NMDA Receptor-Dependent Synaptic Plasticity. Biological Psychiatry |
| Porter-Stransky KA, Petko AK, Karne SL, et al. (2019) Loss of β-arrestin2 in D2 cells alters neuronal excitability in the nucleus accumbens and behavioral responses to psychostimulants and opioids. Addiction Biology. e12823 |
| Martini ML, Liu J, Ray C, et al. (2019) Defining Structure-Functional Selectivity Relationships (SFSR) for a Class of Non-Catechol Dopamine D1 Receptor Agonists. Journal of Medicinal Chemistry |
| Toth K, Slosky LM, Pack TF, et al. (2017) Ghrelin receptor antagonism of hyperlocomotion in cocaine-sensitized mice requires βarrestin-2. Synapse (New York, N.Y.) |
| Zhu L, Rossi M, Cui Y, et al. (2017) Hepatic β-arrestin 2 is essential for maintaining euglycemia. The Journal of Clinical Investigation |
| Urs NM, Gee SM, Pack TF, et al. (2016) Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties. Proceedings of the National Academy of Sciences of the United States of America |
| Urs NM, Peterson SM, Caron MG. (2016) New Concepts in Dopamine D2 Receptor Biased Signaling and Implications for Schizophrenia Therapy. Biological Psychiatry |