James T. Payne, Ph.D
Affiliations: | 2010 | Chemistry, Astronomy | University of Illinois, Urbana-Champaign, Urbana-Champaign, IL |
| 2010-2015 | Chemistry | University of Chicago, Chicago, IL | |
| 2015- | Bioengineering | Stanford University, Palo Alto, CA |
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Parents
Sign in to add mentor| You-Hua Chu | research assistant | 2008-2010 | UIUC (Physics Tree) | |
| Jared C. Lewis | grad student | 2010-2015 | Chicago | |
| (Thesis: "Engineering Halogenases for Selective Functionalization of Bioactive Molecules") | ||||
| Christina D. Smolke | post-doc | 2015- | Stanford | |
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Publications
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| Jamil OK, Cravens A, Payne JT, et al. (2022) Biosynthesis of tetrahydropapaverine and semisynthesis of papaverine in yeast. Proceedings of the National Academy of Sciences of the United States of America. 119: e2205848119 |
| Payne JT, Valentic TR, Smolke CD. (2021) Complete biosynthesis of the bisbenzylisoquinoline alkaloids guattegaumerine and berbamunine in yeast. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Hafner J, Payne J, MohammadiPeyhani H, et al. (2021) A computational workflow for the expansion of heterologous biosynthetic pathways to natural product derivatives. Nature Communications. 12: 1760 |
| Cravens A, Payne J, Smolke CD. (2019) Synthetic biology strategies for microbial biosynthesis of plant natural products. Nature Communications. 10: 2142 |
| Payne JT, Butkovich PH, Gu YF, et al. (2018) Enantioselective Desymmetrization of Methylenedianilines via Enzyme-Catalyzed Remote Halogenation. Journal of the American Chemical Society |
| Payne JT, Andorfer MC, Lewis JC. (2016) Engineering Flavin-Dependent Halogenases. Methods in Enzymology. 575: 93-126 |
| Durak LJ, Payne JT, Lewis JC. (2016) Late-Stage Diversification of Biologically Active Molecules via Chemoenzymatic C-H Functionalization. Acs Catalysis. 6: 1451-1454 |
| Durak LJ, Payne JT, Lewis JC. (2016) Late-Stage Diversification of Biologically Active Molecules via Chemoenzymatic C-H Functionalization Acs Catalysis. 6: 1451-1454 |
| Payne JT, Poor CB, Lewis JC. (2015) Directed evolution of RebH for site-selective halogenation of large biologically active molecules. Angewandte Chemie (International Ed. in English). 54: 4226-30 |
| Payne JT, Lewis JC. (2014) Upgrading nature's tools: Expression enhancement and preparative utility of the halogenase RebH Synlett. 25: 1345-1349 |