Robert M. Immormino, Ph.D.

Affiliations: 
2007 Duke University, Durham, NC 
Area:
Biochemistry
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"Robert Immormino"
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Daniel T. Gewirth grad student 2007 Duke
 (Ligand interaction and regulation in eukaryotic Hsp90 homologs.)
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Publications

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Huck JD, Que NLS, Immormino RM, et al. (2019) NECA derivatives exploit the paralog-specific properties of the Site 3 side pocket of Grp94, the ER Hsp90. The Journal of Biological Chemistry
Immormino RM, Starbird CA, Silversmith RE, et al. (2015) Probing Mechanistic Similarities between Response Regulator Signaling Proteins and Haloacid Dehalogenase Phosphatases. Biochemistry. 54: 3514-27
Chen VB, Arendall WB, Headd JJ, et al. (2012) Chapter 21.6 MolProbity: all-atom structure validation for macromolecular crystallography International Tables For Crystallography
Chen VB, Arendall WB, Headd JJ, et al. (2010) MolProbity: all-atom structure validation for macromolecular crystallography. Acta Crystallographica. Section D, Biological Crystallography. 66: 12-21
Immormino RM, Metzger LE, Reardon PN, et al. (2009) Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design. Journal of Molecular Biology. 388: 1033-42
Headd JJ, Immormino RM, Keedy DA, et al. (2009) Autofix for backward-fit sidechains: using MolProbity and real-space refinement to put misfits in their place. Journal of Structural and Functional Genomics. 10: 83-93
Richardson JS, Schneider B, Murray LW, et al. (2008) RNA backbone: consensus all-angle conformers and modular string nomenclature (an RNA Ontology Consortium contribution). Rna (New York, N.Y.). 14: 465-81
Dollins DE, Warren JJ, Immormino RM, et al. (2007) Structures of GRP94-nucleotide complexes reveal mechanistic differences between the hsp90 chaperones. Molecular Cell. 28: 41-56
Immormino RM, Kang Y, Chiosis G, et al. (2006) Structural and quantum chemical studies of 8-aryl-sulfanyl adenine class Hsp90 inhibitors. Journal of Medicinal Chemistry. 49: 4953-60
Williams AH, Immormino RM, Gewirth DT, et al. (2006) Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide. Proceedings of the National Academy of Sciences of the United States of America. 103: 10877-82
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