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Thomas C. Pochapsky

Affiliations: 
Chemistry Brandeis University, Waltham, MA, United States 
Area:
Physical Chemistry, Biochemistry
Website:
http://www.bio.brandeis.edu/faculty/pochapsky.html
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"Thomas Pochapsky"
Bio:

http://www.bio.brandeis.edu/pochapskylab/Pochapsky_Lab/People.html

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Parents

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William Howard Pirkle grad student 1981-1986 UIUC

Children

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Nitin U. Jain grad student University of Tennessee, Knoxville
Bo OuYang grad student Shanghai institute of biochemistry and cell biology
Patricia Stone Wilkinson grad student 1989-1993 UNH
Xiaomei Ye grad student 1989-1993 Brandeis
Antonio Francisco Pereira de Araujo grad student 1995 Universidade de Brasilia, Brasilia, DF, Brasil
Alexandra Patera grad student 1990-1995 Dartmouth
Gayathri Ratnaswamy grad student 1990-1995 Brandeis
Teresa A. Lyons grad student 1990-1996 Brandeis
Miklos Kuti grad student 1997 Brandeis
Huaping Mo grad student 1998 Purdue
Anping Wang grad student 1998 Brandeis
Sophia Kazanis grad student 1999 Brandeis
Christine Hofstetter grad student 2001 Brandeis
John C. Obenauer grad student 2001 Brandeis
Milka Kostic grad student 2004 Brandeis
Tingting Ju grad student 2005 Brandeis
Julie Y. Wei grad student 2006 Brandeis
Marina Dang grad student 2010 Brandeis
Iva Perovic grad student 2012 Brandeis
Drew R. Tietz grad student 2009-2015 Brandeis
Allison Colthart grad student 2010-2015 Brandeis

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Publications

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Wong NR, Sundar R, Kazanis S, et al. (2023) Conformational heterogeneity suggests multiple substrate binding modes in CYP106A2. Journal of Inorganic Biochemistry. 241: 112129
Pochapsky TC. (2020) A dynamic understanding of cytochrome P450 structure and function through solution NMR. Current Opinion in Biotechnology. 69: 35-42
Pochapsky TC, Pochapsky SS. (2019) What Your Crystal Structure Will Not Tell You about Enzyme Function. Accounts of Chemical Research
Wong NR, Liu X, Lloyd H, et al. (2018) A new approach to understanding structure-function relationships in cytochromes P450 by targeting terpene metabolism in the wild. Journal of Inorganic Biochemistry. 188: 96-101
Asciutto EK, Pochapsky TC. (2018) Some Surprising Implications of NMR-directed Simulations of Substrate Recognition and Binding by Cytochrome P450 (CYP101A1). Journal of Molecular Biology. 430: 1295-1310
Tietz DR, Colthart AM, Sondej Pochapsky S, et al. (2017) Substrate recognition by two different P450s: Evidence for conserved roles in a common fold. Scientific Reports. 7: 13581
Deshpande AR, Pochapsky TC, Ringe D. (2017) The Metal Drives the Chemistry: Dual Functions of Acireductone Dioxygenase. Chemical Reviews
Tietz DR, Podust LM, Sherman DH, et al. (2017) Solution conformations and dynamics of substrate-bound cytochrome P450 MycG. Biochemistry
Pochapsky TC, Wong N, Zhuang Y, et al. (2017) NADH reduction of nitroaromatics as a probe for residual ferric form high-spin in a cytochrome P450. Biochimica Et Biophysica Acta
Deshpande AR, Pochapsky TC, Petsko GA, et al. (2017) Dual chemistry catalyzed by human acireductone dioxygenase. Protein Engineering, Design & Selection : Peds
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