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Marjorie F. Lou

Affiliations: 
Biochemistry The University of Nebraska - Lincoln, Lincoln, NE 
Area:
Cell Biology, Ophthalmology, Molecular Biology
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"Marjorie Lou"
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Children

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Kate C. Chen grad student 2006 University of Nebraska - Lincoln
Namal P. Malimbada Liyanage grad student 2009 University of Nebraska - Lincoln

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Publications

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Lou MF. (2022) Glutathione and Glutaredoxin in Redox Regulation and Cell Signaling of the Lens. Antioxidants (Basel, Switzerland). 11
Daszynski DM, Santhoshkumar P, Phadte AS, et al. (2019) Failure of Oxysterols Such as Lanosterol to Restore Lens Clarity from Cataracts. Scientific Reports. 9: 8459
Zhang J, Yan H, Lou MF. (2017) Does oxidative stress play any role in diabetic cataract formation? ----Re-evaluation using a thioltransferase gene knockout mouse model. Experimental Eye Research
Wei M, Xing KY, Fan YC, et al. (2015) Loss of thiol repair systems in human cataractous lenses. Investigative Ophthalmology & Visual Science. 56: 598-605
Upadhyaya B, Tian X, Wu H, et al. (2015) Expression and distribution of thiol-regulating enzyme glutaredoxin 2 (GRX2) in porcine ocular tissues. Experimental Eye Research. 130: 58-65
Wu H, Yu Y, David L, et al. (2014) Glutaredoxin 2 (Grx2) gene deletion induces early onset of age-dependent cataracts in mice. The Journal of Biological Chemistry. 289: 36125-39
Mailloux RJ, Xuan JY, Beauchamp B, et al. (2013) Glutaredoxin-2 is required to control proton leak through uncoupling protein-3. The Journal of Biological Chemistry. 288: 8365-79
Yu Y, Xing K, Badamas R, et al. (2013) Overexpression of thioredoxin-binding protein 2 increases oxidation sensitivity and apoptosis in human lens epithelial cells. Free Radical Biology & Medicine. 57: 92-104
Zhang P, Xing K, Randazzo J, et al. (2012) Osmotic stress, not aldose reductase activity, directly induces growth factors and MAPK signaling changes during sugar cataract formation. Experimental Eye Research. 101: 36-43
Wu H, Lin L, Giblin F, et al. (2011) Glutaredoxin 2 knockout increases sensitivity to oxidative stress in mouse lens epithelial cells. Free Radical Biology & Medicine. 51: 2108-17
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