Wanda Lee, Ph.D.

Affiliations: 
2008 Florida Atlantic University, Boca Raton, FL, United States 
Area:
Molecular Biology, Cell Biology, Biochemistry
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Marc Kantorow grad student 2008 Florida Atlantic University
 (Peroxiredoxin 3 and Methionine sulfoxide reductase A are essential for lens cell viability by preserving lens cell mitochondrial function through repair of Cytochrome c.)
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Publications

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Kantorow M, Lee W, Chauss D. (2012) Focus on Molecules: methionine sulfoxide reductase A. Experimental Eye Research. 100: 110-1
Brennan LA, Lee W, Kantorow M. (2010) TXNL6 is a novel oxidative stress-induced reducing system for methionine sulfoxide reductase a repair of α-crystallin and cytochrome C in the eye lens. Plos One. 5: e15421
KANTOROW M, BRENNAN L, MCGREAL R, et al. (2010) MsrA repair of Cytochrome c and α-crystallin links chaperone and oxidative repair pathways with mitochondrial protection and apoptotic control in lens cells. Acta Ophthalmologica. 88: 0-0
Brennan LA, Lee W, Giblin FJ, et al. (2009) Methionine sulfoxide reductase A (MsrA) restores alpha-crystallin chaperone activity lost upon methionine oxidation. Biochimica Et Biophysica Acta. 1790: 1665-72
Brennan LA, Lee W, Cowell T, et al. (2009) Deletion of mouse MsrA results in HBO-induced cataract: MsrA repairs mitochondrial cytochrome c. Molecular Vision. 15: 985-99
Lee W, Wells T, Kantorow M. (2007) Localization and H2O2-specific induction of PRDX3 in the eye lens. Molecular Vision. 13: 1469-74
Marchetti MA, Lee W, Cowell TL, et al. (2006) Silencing of the methionine sulfoxide reductase A gene results in loss of mitochondrial membrane potential and increased ROS production in human lens cells Experimental Eye Research. 83: 1281-1286
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