Madhavika N. Serasinghe, Ph.D.

Affiliations: 
2009 University of Rochester, Rochester, NY 
Area:
Cell Biology, Molecular Biology, Biochemistry
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"Madhavika Serasinghe"
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Yisang Yoon grad student 2009 Rochester
 (Identification of novel molecular interactions of the mitochondrial fission protein hFis1: Insight into its action mechanism and therapeutic potential.)
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Publications

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Elkholi R, Abraham-Enachescu I, Trotta AP, et al. (2019) MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network. Molecular Cell
Abbate F, Badal B, Mendelson K, et al. (2018) FBXW7 regulates a mitochondrial transcription program by modulating MITF. Pigment Cell & Melanoma Research
Serasinghe MN, Gelles JD, Li K, et al. (2018) Dual suppression of inner and outer mitochondrial membrane functions augments apoptotic responses to oncogenic MAPK inhibition. Cell Death & Disease. 9: 29
Hogstad B, Berres ML, Chakraborty R, et al. (2017) RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions. The Journal of Experimental Medicine
Trotta AP, Gelles JD, Serasinghe MN, et al. (2017) Disruption of mitochondrial electron transport chain function potentiates the pro-apoptotic effects of MAPK inhibition. The Journal of Biological Chemistry
Serasinghe MN, Chipuk JE. (2017) Mitochondrial Fission in Human Diseases. Handbook of Experimental Pharmacology
Rimmelé P, Liang R, Bigarella CL, et al. (2015) Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3. Embo Reports
Gelles JD, Elkholi R, Serasinghe MN, et al. (2015) From zero to sixty: cell death signaling in the city that never sleeps. Oncogene
Wieder SY, Serasinghe MN, Sung JC, et al. (2015) Activation of the Mitochondrial Fragmentation Protein DRP1 Correlates with BRAF(V600E) Melanoma. The Journal of Investigative Dermatology
Serasinghe MN, Wieder SY, Renault TT, et al. (2015) Mitochondrial division is requisite to RAS-induced transformation and targeted by oncogenic MAPK pathway inhibitors. Molecular Cell. 57: 521-36
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