Shubhada Sharma, Ph.D.

Affiliations: 
2008 Chemistry State University of New York at Binghamton, Vestal, NY, United States 
Area:
Biochemistry
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"Shubhada Sharma"
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Parents

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Susan L. Bane grad student 2008 SUNY Binghamton
 (Molecular mechanisms of antimicrotubule agents, paclitaxel and colchicine.)
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Publications

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Sharma S, Lagisetti C, Poliks B, et al. (2013) Dissecting paclitaxel-microtubule association: quantitative assessment of the 2'-OH group. Biochemistry. 52: 2328-36
Zhan W, Jiang Y, Sharma S, et al. (2011) C6-C8 bridged epothilones: consequences of installing a conformational lock at the edge of the macrocycle. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 14792-804
Sharifi N, Qi J, Bane S, et al. (2011) Erratum: Survivin is not induced by novel taxanes (Molecular Pharmaceutics (2010) 7: 6 (2216-2223)) Molecular Pharmaceutics. 8
Sharifi N, Qi J, Bane S, et al. (2010) Survivin is not induced by novel taxanes. Molecular Pharmaceutics. 7: 2216-23
Chen QH, Ganesh T, Jiang Y, et al. (2010) Novel epothilone lactones by an unusual diversion of the Grubbs' metathesis reaction. Chemical Communications (Cambridge, England). 46: 2019-21
Sharma S, Poliks B, Chiauzzi C, et al. (2010) Characterization of the colchicine binding site on avian tubulin isotype betaVI. Biochemistry. 49: 2932-42
Hodge M, Chen QH, Bane S, et al. (2009) Synthesis and bioactivity of a side chain bridged paclitaxel: A test of the T-Taxol conformation. Bioorganic & Medicinal Chemistry Letters. 19: 2884-7
Sharma S, Ganesh T, Kingston DG, et al. (2007) Promotion of tubulin assembly by poorly soluble taxol analogs. Analytical Biochemistry. 360: 56-62
Tang S, Yang C, Brodie P, et al. (2006) Bridging converts a noncytotoxic nor-paclitaxel derivative to a cytotoxic analogue by constraining it to the T-Taxol conformation. Organic Letters. 8: 3983-6
Ganesh T, Norris A, Sharma S, et al. (2006) Design, synthesis, and bioactivity of simplified paclitaxel analogs based on the T-Taxol bioactive conformation. Bioorganic & Medicinal Chemistry. 14: 3447-54
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