Suzanne E. Wardell, Ph.D.

Affiliations: 
2004 University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Molecular Biology
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Dean P. Edwards grad student 2004 University of Colorado, Denver
 (Jun dimerization protein 2 coactivates transactivation by the progesterone receptor N-domain by a novel allosteric mechanism.)
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Publications

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Chakraborty B, Chakraborty P, Brown MC, et al. (2024) Estrogens increase cancer cell efferocytosis to establish an immunosuppressive tumor microenvironment. Biorxiv : the Preprint Server For Biology
Killarney ST, Mesa G, Washart R, et al. (2024) PKN2 is a dependency of the mesenchymal-like cancer cell state. Cancer Discovery
Artham S, Juras PK, Goyal A, et al. (2024) Estrogen signaling suppresses tumor-associated tissue eosinophilia to promote breast tumor growth. Science Advances. 10: eadp2442
Safi R, Wardell SE, Watkinson P, et al. (2024) Androgen receptor monomers and dimers regulate opposing biological processes in prostate cancer cells. Nature Communications. 15: 7675
Price MJ, Nguyen AD, Haines C, et al. (2024) UDP-6-glucose dehydrogenase in hormonally responsive breast cancers. Biorxiv : the Preprint Server For Biology
Haines CN, Wardell SE, McDonnell DP. (2021) Current and emerging estrogen receptor-targeted therapies for the treatment of breast cancer. Essays in Biochemistry
McDonnell DP, Wardell SE, Chang CY, et al. (2021) Next-Generation Endocrine Therapies for Breast Cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2003565
Andreano KJ, Baker JG, Park S, et al. (2020) The dysregulated pharmacology of clinically relevant ESR1 mutants is normalized by ligand-activated WT receptor. Molecular Cancer Therapeutics
Andreano KJ, Wardell SE, Baker JG, et al. (2020) G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer. Breast Cancer Research and Treatment
Wardell SE, Yllanes AP, Chao CA, et al. (2019) Correction to: Pharmacokinetic and pharmacodynamic analysis of fulvestrant in preclinical models of breast cancer to assess the importance of its estrogen receptor-α degrader activity in antitumor efficacy. Breast Cancer Research and Treatment
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