Eliot M. Rosen

Affiliations: 
Biochemistry & Molecular Georgetown University, Washington, DC 
Area:
Biochemistry, Cell Biology
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"Eliot Rosen"
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Publications

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Nathan S, Ma Y, Tomita YA, et al. (2017) BRCA1-mimetic compound NSC35446.HCl inhibits IKKB expression by reducing estrogen receptor-α occupancy in the IKKB promoter and inhibits NF-κB activity in antiestrogen-resistant human breast cancer cells. Breast Cancer Research and Treatment
Nathan S, Rosen EM. (2017) Abstract 3602: Novel BRCA1 mimetic 35446HCl inhibits growth of anti estrogen resistant breast cancer cells through the NF-κB pathway Cancer Research. 77: 3602-3602
Ma Y, Preet A, Tomita Y, et al. (2015) A new class of small molecule estrogen receptor-alpha antagonists that overcome anti-estrogen resistance. Oncotarget
Ma Y, Tomita Y, Preet A, et al. (2014) Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α. Molecular Endocrinology (Baltimore, Md.). 28: 1971-86
Rosen EM, Pishvaian MJ. (2014) Targeting the BRCA1/2 tumor suppressors. Current Drug Targets. 15: 17-31
Xu JY, Meng QH, Chong Y, et al. (2013) Sanguinarine is a novel VEGF inhibitor involved in the suppression of angiogenesis and cell migration. Molecular and Clinical Oncology. 1: 331-336
Fan S, Meng Q, Xu J, et al. (2013) DIM (3,3'-diindolylmethane) confers protection against ionizing radiation by a unique mechanism. Proceedings of the National Academy of Sciences of the United States of America. 110: 18650-5
Rosen EM. (2013) BRCA1 in the DNA damage response and at telomeres. Frontiers in Genetics. 4: 85
Ma Y, Preet A, Hu C, et al. (2013) Abstract 5574: Development of novel breast cancer therapeutics for anti-estrogen resistant breast cancer. Cancer Research. 73: 5574-5574
Oliveira EOD, Ma Y, Tomita Y, et al. (2013) Abstract 2458: Discovery and development of novel 4-aminopyrimidines (A9 analogs) as potential BRCA1-mimetic drugs for the treatment of breast cancer. Cancer Research. 73: 2458-2458
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