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JoAnn Trejo

Affiliations: 
Pharmacology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Cell Biology, Biochemistry
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"JoAnn Trejo"
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May M. Paing grad student 2005 UNC Chapel Hill
Breann L. Wolfe grad student 2007 UNC Chapel Hill
Angela Russo grad student 2009 UNC Chapel Hill
Tiffany K. Ricks grad student 2010 UNC Chapel Hill

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Publications

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Cheng N, Trejo J. (2023) An siRNA library screen identifies CYLD and USP34 as deubiquitinases that regulate GPCR-p38 MAPK signaling and distinct inflammatory responses. The Journal of Biological Chemistry. 105370
Birch CA, Wedegaertner H, Orduña-Castillo LB, et al. (2023) Endothelial APC/PAR1 distinctly regulates cytokine-induced pro-inflammatory VCAM-1 expression. Frontiers in Molecular Biosciences. 10: 1211597
Wedegaertner H, Bosompra O, Kufareva I, et al. (2023) Divergent regulation of α-arrestin ARRDC3 function by ubiquitination. Molecular Biology of the Cell. mbcE23020055
Molinar-Inglis O, Wozniak JM, Grimsey NJ, et al. (2022) Phosphoproteomic analysis of thrombin- and p38 MAPK-regulated signaling networks in endothelial cells. The Journal of Biological Chemistry. 101801
Molinar-Inglis O, Birch CA, Nicholas D, et al. (2021) aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete, β-arrestin-2-mediated SphK1-S1PR1-Akt signaling axis. Proceedings of the National Academy of Sciences of the United States of America. 118
Wedegaertner H, Pan WA, Gonzalez CC, et al. (2021) The α-arrestin ARRDC3 is an Emerging Multifunctional Adaptor Protein in Cancer. Antioxidants & Redox Signaling
Arakaki AKS, Pan WA, Wedegaertner H, et al. (2021) α-arrestin ARRDC3 tumor suppressor function is linked to GPCR-induced TAZ activation and breast cancer metastasis. Journal of Cell Science
Patwardhan A, Cheng N, Trejo J. (2021) Post-Translational Modifications of G Protein-Coupled Receptors Control Cellular Signaling Dynamics in Space and Time. Pharmacological Reviews. 73: 120-151
Birch CA, Molinar-Inglis O, Trejo J. (2021) Subcellular hot spots of GPCR signaling promote vascular inflammation. Current Opinion in Endocrine and Metabolic Research. 16: 37-42
Zhou X, Zhong Y, Molinar-Inglis O, et al. (2020) Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus. Nature Communications. 11: 6088
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