Lulu Huang, Ph.D.
Affiliations: | 2009 | The University of Texas Graduate School of Biomedical Sciences at Houston |
Area:
Molecular BiologyGoogle:
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Parents
Sign in to add mentorMiles F. Wilkinson | grad student | 2009 | The University of Texas Graduate School of Biomedical Sciences at Houston | |
(Nonsense -mediated decay: A branched and regulated pathway.) |
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Publications
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Dou X, Huang L, Xiao Y, et al. (2023) METTL14 is a chromatin regulator independent of its RNA N6-methyladenosine methyltransferase activity. Protein & Cell |
Sanderlin EJ, Keenan MM, Mense M, et al. (2022) CFTR mRNAs with nonsense codons are degraded by the SMG6-mediated endonucleolytic decay pathway. Nature Communications. 13: 2344 |
Christopher Boyd A, Guo S, Huang L, et al. (2020) New approaches to genetic therapies for cystic fibrosis. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society |
Huang L, Aghajan M, Quesenberry T, et al. (2019) Targeting Translation Termination Machinery with Antisense Oligonucleotides for Diseases Caused by Nonsense Mutations. Nucleic Acid Therapeutics |
Keenan MM, Huang L, Jordan NJ, et al. (2019) Nonsense Mediated RNA Decay Pathway Inhibition Restores Expression and Function of W1282X CFTR. American Journal of Respiratory Cell and Molecular Biology |
Huang L, Low A, Damle SS, et al. (2018) Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations. Genome Biology. 19: 4 |
Huang L, Shum EY, Jones SH, et al. (2017) A Upf3b-mutant mouse model with behavioral and neurogenesis defects. Molecular Psychiatry |
Shum EY, Jones SH, Shao A, et al. (2016) The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay. Cell |
Huang L, Damle SS, Booten S, et al. (2015) Partial Hepatectomy Induced Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration. Plos One. 10: e0132798 |
Karam R, Lou CH, Kroeger H, et al. (2015) The unfolded protein response is shaped by the NMD pathway. Embo Reports. 16: 599-609 |