Beatriz Russell, Ph.D.

Affiliations: 
2010 University of Cincinnati, Cincinnati, OH 
Area:
Biochemistry
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"Beatriz Russell"
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Joanna Groden grad student 2010 University of Cincinnati
 (Interactions with topoisomerase IIalpha enhance the unwinding activity of the BLM helicase on recombination substrates and are necessary for preventing chromosome breakage.)
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Publications

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Russell B, Bhattacharyya S, Keirsey J, et al. (2011) Chromosome breakage is regulated by the interaction of the BLM helicase and topoisomerase IIalpha. Cancer Research. 71: 561-71
Bhattacharyya S, Keirsey J, Russell B, et al. (2009) Telomerase-associated protein 1, HSP90, and topoisomerase IIalpha associate directly with the BLM helicase in immortalized cells using ALT and modulate its helicase activity using telomeric DNA substrates. The Journal of Biological Chemistry. 284: 14966-77
Goudelock DM, Jiang K, Pereira E, et al. (2003) Regulatory interactions between the checkpoint kinase Chk1 and the proteins of the DNA-dependent protein kinase complex. The Journal of Biological Chemistry. 278: 29940-7
Jiang K, Pereira E, Maxfield M, et al. (2003) Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345. The Journal of Biological Chemistry. 278: 25207-17
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