John M. Kyriakis

Affiliations: 
Biochemistry Sackler School of Graduate Biomedical Sciences (Tufts University) 
Area:
Biochemistry, Molecular Biology, Oncology
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"John Kyriakis"
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Publications

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Kyriakis JM. (2014) In the beginning, there was protein phosphorylation Journal of Biological Chemistry. 289: 9460-9462
Zhang Y, Welzig CM, Picard KL, et al. (2014) Glycogen synthase kinase-3β inhibition ameliorates cardiac parasympathetic dysfunction in type 1 diabetic Akita mice. Diabetes. 63: 2097-113
Kyriakis JM, Avruch J. (2012) Mammalian MAPK signal transduction pathways activated by stress and inflammation: A 10-year update Physiological Reviews. 92: 689-737
Georgescu SP, Aronovitz MJ, Iovanna JL, et al. (2011) Decreased metalloprotease 9 induction, cardiac fibrosis, and higher autophagy after pressure overload in mice lacking the transcriptional regulator p8. American Journal of Physiology. Cell Physiology. 301: C1046-56
Kong DK, Georgescu SP, Kyriakis JM, et al. (2010) Deficiency of transcriptional regulator p8 induces autophagy and causes impaired cardiac function. Autophagy. 6: 652-654
Chadee DN, Kyriakis JM. (2010) Activation of SAPK/JNKs in vitro. Methods in Molecular Biology (Clifton, N.J.). 661: 59-73
Kilili GK, Kyriakis JM. (2010) Mammalian Ste20-like kinase (Mst2) indirectly supports Raf-1/ERK pathway activity via maintenance of protein phosphatase-2A catalytic subunit levels and consequent suppression of inhibitory Raf-1 phosphorylation. The Journal of Biological Chemistry. 285: 15076-87
Kong DK, Georgescu SP, Cano C, et al. (2010) Deficiency of the transcriptional regulator p8 results in increased autophagy and apoptosis, and causes impaired heart function. Molecular Biology of the Cell. 21: 1335-49
Kong DK, Georgescu SP, Kyriakis JM, et al. (2010) Deficiency of transcriptional regulator p8 induces autophagy and causes impaired cardiac function Autophagy. 6: 652-654
Zhong J, Gavrilescu LC, Molnár A, et al. (2009) GCK is essential to systemic inflammation and pattern recognition receptor signaling to JNK and p38. Proceedings of the National Academy of Sciences of the United States of America. 106: 4372-7
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