Jeremy A. Goettel, Ph.D.
Affiliations: | 2010 | Vanderbilt University, Nashville, TN |
Area:
Cell Biology, BiochemistryGoogle:
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Parents
Sign in to add mentorSteven K. Hanks | grad student | 2010 | Vanderbilt | |
(Kinase suppressor of Ras 1 is a functional protein kinase and protects from experimental colitis in mice by regulating T lymphocyte IFN-gamma production.) |
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Publications
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Tyagi RK, Jacobse J, Li J, et al. (2021) HLA-Restriction of Human Treg Cells Is Not Required for Therapeutic Efficacy of Low-Dose IL-2 in Humanized Mice. Frontiers in Immunology. 12: 630204 |
Jacobse J, Li J, Tyagi RK, et al. (2020) 933 Interleukin-23 Receptor Signaling Modulates The Stability And Function Of Forkhead Box P3 Positive Regulatory T Cells Gastroenterology. 158 |
Tyagi RK, Li J, Jacobse J, et al. (2019) Humanized Mouse Models of Genetic Immune Disorders and Hematological Malignancies. Biochemical Pharmacology. 113671 |
Tsou A, Goettel J, Biswas A, et al. (2019) P155 Elucidating Interactions Between The Immune System And The Gut Microbiota In A Reductionist Murine Model Of Inflammatory Bowel Disease Gastroenterology. 156 |
Ryzhakov G, West NR, Franchini F, et al. (2018) Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis. Nature Communications. 9: 3797 |
Biswas A, Shouval DS, Griffith A, et al. (2018) WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis. Nature Communications. 9: 1779 |
Shouval DS, Konnikova L, Griffith AE, et al. (2017) Enhanced TH17 Responses in Patients with IL10 Receptor Deficiency and Infantile-onset IBD. Inflammatory Bowel Diseases |
Redhu NS, Bakthavatchalu V, Conaway EA, et al. (2017) Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor. Elife. 6 |
Goettel J, Kotlarz D, Illig D, et al. (2017) O-011 Low-dose IL-2 Administration Expands Human Regulatory T Cells in Patients with UC and Humanized Mice and Protects Against Experimental Colitis. Inflammatory Bowel Diseases. 23: S4 |
Thiagarajah JR, Chang J, Goettel JA, et al. (2017) Aquaporin-3 mediates hydrogen peroxide-dependent responses to environmental stress in colonic epithelia. Proceedings of the National Academy of Sciences of the United States of America |