Pankaj K. Singh, Ph.D.

Affiliations: 
2007 University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Biochemistry, Oncology, Molecular Biology
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"Pankaj Singh"
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Michael A. Hollingsworth grad student 2007 University of Nebraska Medical Center
 (Phosphorylation-mediated signaling of MUC1 cytoplasmic tail in pancreatic cancer.)
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Publications

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Treekitkarnmongkol W, Solis LM, Sankaran D, et al. (2024) eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer. Science Signaling. 17: eadh4475
Murthy D, Attri KS, Shukla SK, et al. (2024) Cancer-associated fibroblast-derived acetate promotes pancreatic cancer development by altering polyamine metabolism via the ACSS2-SP1-SAT1 axis. Nature Cell Biology
Chumak V, Rajacharya GH, Singh PK. (2024) Metabolomic Investigations into Hypoxia-Mediated Metabolic Reprogramming of Pancreatic Cancer Cells. Methods in Molecular Biology (Clifton, N.J.). 2755: 191-200
Singh PK, Mehla K. (2023) LXR Signaling-Mediated Cholesterol Metabolism Reprogramming Regulates Cancer Cell Metastasis. Cancer Research. 83: 1759-1761
Mullen NJ, Shukla SK, Thakur R, et al. (2023) DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation. Biorxiv : the Preprint Server For Biology
Mullen NJ, Singh PK. (2023) Nucleotide metabolism: a pan-cancer metabolic dependency. Nature Reviews. Cancer. 23: 275-294
Mullen NJ, Thakur R, Shukla SK, et al. (2022) ENT1 blockade by CNX-774 overcomes resistance to DHODH inhibition in pancreatic cancer. Cancer Letters. 552: 215981
Gupta K, Jones JC, Farias VA, et al. (2022) Identification of Synergistic Drug Combinations to Target KRAS-Driven Chemoradioresistant Cancers Utilizing Tumoroid Models of Colorectal Adenocarcinoma and Recurrent Glioblastoma. Frontiers in Oncology. 12: 840241
Xu PC, You M, Yu SY, et al. (2022) Visceral adipose tissue remodeling in pancreatic ductal adenocarcinoma cachexia: the role of activin A signaling. Scientific Reports. 12: 1659
King RJ, Shukla SK, He C, et al. (2022) CD73 induces GM-CSF/MDSC-mediated suppression of T cells to accelerate pancreatic cancer pathogenesis. Oncogene
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